Evidence map›Paper›PMID 34752080›Full record

ArticleACS biomaterials science & engineering2021

Measuring the Effects of Cytokines on the Modification of Pericellular Rheology by Human Mesenchymal Stem Cells.

Maryam Daviran, John A McGlynn, Jenna A Catalano, Hannah E Knudsen, Kilian J Druggan, Kiera J Croland, Amanda Stratton, Kelly M Schultz

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maryam DaviranDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
John A McGlynnDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Jenna A CatalanoDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Hannah E KnudsenDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Kilian J DrugganDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Kiera J CrolandDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Amanda StrattonDepartment of Bioengineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.
Kelly M SchultzDepartment of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Drive, Iacocca Hall, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0001-9040-126X
Lehigh University · US

Funding

Understanding how MSCs controllably remodel their environmentR15GM119065 · NIGMS · LEHIGH UNIVERSITY · PI SCHULTZ, KELLY M · 2016 to 2019
$895k
NIGMS NIH HHS R15 GM119065
6 · The paper itself

Abstract

Implantable hydrogels are designed to treat wounds by providing structure and delivering additional cells to damaged tissue. These materials must consider how aspects of the native wound, including environmental chemical cues, affect and instruct delivered cells. One cell type researchers are interested in delivering are human mesenchymal stem cells (hMSCs) due to their importance in healing. Wound healing involves recruiting and coordinating a variety of cells to resolve a wound. hMSCs coordinate the cellular response and are signaled to the wound by cytokines, including transforming growth factor-β (TGF-β) and tumor necrosis factor-α (TNF-α), present

Indexed as

Mesenchymal Stem CellsCytokinesExtracellular MatrixHumansHydrogelsRheologyCytokinesHydrogelscytokineshuman mesenchymal stem cellshydrogelsmultiple particle tracking microrheology

Identifiers

PMID34752080
PMCPMC8886793
OpenAlexW3211438885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.