Evidence map›Paper›PMID 34751987›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2022

Recent Progress in Materials Chemistry to Advance Flexible Bioelectronics in Medicine.

Gaurav Balakrishnan, Jiwoo Song, Chenchen Mou, Christopher J Bettinger

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Design, Construction, and Application of Implantable Fiber Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Review
  4. A Thin Film Transistor Backplane for Scalable Chronic Neural Interfaces.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Recent Progress of Soft and Bioactive Materials in Flexible Bioelectronics.Cyborg and bionic systems (Washington, D.C.) · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Motion artefact management for soft bioelectronics.Nature reviews bioengineering · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gaurav BalakrishnanCarnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, 15213, USA.ORCID https://orcid.org/0000-0002-7671-4048
Jiwoo SongCarnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, 15213, USA.
Chenchen MouCarnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, 15213, USA.
Christopher J BettingerCarnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, 15213, USA.ORCID https://orcid.org/0000-0002-6564-5681

Funding

Adhesive Transient Strain Sensors for Monitoring Post-Cardiotomy HemodynamicsR21EB028418 · NIBIB · ALLEGHENY-SINGER RESEARCH INSTITUTE · PI HALBREINER, MICHAEL SCOTT · 2020 to 2022
$596k
Hydrogel Multielectrode Arrays for Therapeutic Peripheral Nerve StimulationR21NS095250 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI BETTINGER, CHRISTOPHER JOHN · 2015 to 2016
$409k
Microstructured Intestinal Retentive Devices for Sustained Oral DeliveryR21EB026073 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI BETTINGER, CHRISTOPHER JOHN · 2019 to 2021
$386k
NIBIB NIH HHS R21 EB026073NIBIB NIH HHS R21 EB028418NIH HHS R21EB026073NIH HHS R21EB028418NINDS NIH HHS R21 NS095250
6 · The paper itself

Abstract

Designing bioelectronic devices that seamlessly integrate with the human body is a technological pursuit of great importance. Bioelectronic medical devices that reliably and chronically interface with the body can advance neuroscience, health monitoring, diagnostics, and therapeutics. Recent major efforts focus on investigating strategies to fabricate flexible, stretchable, and soft electronic devices, and advances in materials chemistry have emerged as fundamental to the creation of the next generation of bioelectronics. This review summarizes contemporary advances and forthcoming technical challenges related to three principal components of bioelectronic devices: i) substrates and structural materials, ii) barrier and encapsulation materials, and iii) conductive materials. Through notable illustrations from the literature, integration and device fabrication strategies and associated challenges for each material class are highlighted.

Indexed as

Wearable Electronic DevicesElectronicsHumansbioresorbable electronicsencapsulationextensible conductorsflexible bioelectronicsmaterials chemistrysoft electronics

Identifiers

PMID34751987
PMCPMC8917047

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.