ReviewAmerican journal of clinical dermatology2022
Effects of Topical Retinoids on Acne and Post-inflammatory Hyperpigmentation in Patients with Skin of Color: A Clinical Review and Implications for Practice.
Review in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Bridging Gaps in Malaysian Acne Vulgaris Guidelines: Advisory Statements on Trifarotene for Facial and Truncal Acne.Journal of cosmetic dermatology · 2026Guideline
- Prevention of Post-Inflammatory Hyperpigmentation in Skin of Colour: A Systematic Review.The Australasian journal of dermatology · 2025Pooled it
- Treatment of Post-Inflammatory Hyperpigmentation in Skin of Colour: A Systematic Review.Journal of cutaneous medicine and surgeryPooled it
- Patient Insights on Acne Hyperpigmentation, Trifarotene, and Skincare: 6-Month, LEAP Phase 4 Qualitative Exit Interview Findings.The patient · 2026Trial
- Efficacy and Tolerability of a Novel Cosmetic and Over-the-Counter Facial Acne Regimen Versus a Prescription Treatment.Journal of cosmetic dermatology · 2025Trial
- Expert Consensus on the Role of Dermocosmetics in Acne Management in the United Arab Emirates.Dermatology and therapy · 2026Article
- The Evolution of Topical Retinoids in Dermatology: A Cornerstone of Acne Management (1971-2025).The Journal of clinical and aesthetic dermatology · 2026Review
- Cutaneous Aging in Skin of Color: A Narrative Review.American journal of clinical dermatology · 2026Review
- Acne vulgaris: a clinical update.Australian prescriber · 2026Review
- The Latest Advances in Rosacea Treatment: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Post-inflammatory Hyperpigmentation in Skin of Color: Emerging Therapies and Treatment Algorithms.Cureus · 2026Review
- Evaluation of the Efficacy of a 2-MNG-Containing Serum on Improving Skin Tone and Hyperpigmentation.Dermatology and therapy · 2026Article
- Development, Stability, and Clinical Efficacy of an Oil-in-Serum Formulation with Olive Extract Standardized in Hydroxytyrosol for Post-Inflammatory Hyperpigmentation Treatment.AAPS PharmSciTech · 2026Article
- Exposome involvement in the development of acne vulgaris.Frontiers in immunology · 2026Review
- Rebalancing the Skin: The Microbiome, Acne Pathogenesis, and the Future of Natural and Synthetic Therapies.Molecules (Basel, Switzerland) · 2025Review
- An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.Journal of clinical medicine · 2025Review
- A Prospective Study Comparing Clinical Efficacy of 30% Mandelic Acid Peel Versus 30% Lactic Acid Peel in Periorbital Melanosis.Indian dermatology online journal · 2025Article
- Native Collagen for Surgical Wound and Scar Prevention-A Six-Case Clinical Series.Journal of clinical medicine · 2025Article
- PRACT-India: Practical Recommendations on Acne Care and Medical Treatment in India-A Modified Delphi Consensus.Antibiotics (Basel, Switzerland) · 2025Article
- Acne-induced Post-inflammatory Hyperpigmentation: From Grading to Treatment.Acta dermato-venereologica · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne is a common cause for post-inflammatory hyperpigmentation (PIH), particularly in patients with skin of color (SOC), and PIH is often more distressing to patients than the acne itself. Topical retinoids are approved for the treatment of acne and for pigmentation disorders such as melasma or mottled hyperpigmentation associated with photodamage; moreover, they have been shown to reduce hyperpigmentation in patients with SOC. Therefore, treatment with topical retinoids should be started as early as possible unless contraindicated. Use of novel formulations or application of commonly recommended moisturizers may help reduce irritation. Combining retinoids with other topical agents and procedures such as superficial chemical peels can help to improve hyperpigmentation. Primary acne lesions are likely to improve weeks before PIH resolves and helping patients manage their expectations may reduce frustration. Providing clinicians and researchers with more education about the presentation and management of dermatologic conditions in patients with SOC is also recommended.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.