Evidence map›Paper›PMID 34751835›Full record

ReviewCurrent oncology reports2021

Treatment Perspectives for Ovarian Cancer in Europe and the United States: Initial Therapy and Platinum-Sensitive Recurrence after PARP Inhibitors or Bevacizumab Therapy.

Alexandra Lainé, Travis T Sims, Olivia Le Saux, Isabelle Ray-Coquard, Robert L Coleman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alexandra LainéCentre Léon Bérard, University Claude Bernard Lyon I, Lyon, France. alexandra.laine2@lyon.unicancer.fr.ORCID 0000-0002-8367-6115
Travis T SimsDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Olivia Le SauxCentre Léon Bérard, University Claude Bernard Lyon I, Lyon, France.
Isabelle Ray-CoquardCentre Léon Bérard, University Claude Bernard Lyon I, Lyon, France.
Robert L ColemanGynecologic Oncology, US Oncology Research, The Woodlands, TX, USA.
Université Claude Bernard Lyon 1 · FRThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAlthough the survival rate of patients with ovarian cancer (OC) has significantly improved, OC is still one of the most common causes of gynecologic cancer death in women worldwide. The current advances in primary treatment are based on recent regulatory approvals and recurrency of such treatments, challenging the development of a unified approach to care. Herein, we examine how integration of these new approaches is applied to patient's treatment. RECENT

findingsWe and others have recently reported clinical trials using bevacizumab and/or inhibitors of Poly (ADP-ribose) polymerase (PARP), which have greatly affected the change in first-line treatments for OC. As first-line therapy has evolved, therapeutic agents once designated for recurrent disease are increasingly being incorporated, changing our standard of care following previously indexed trials. Here, we provide an overview of the current treatment for OC patients, and we highlight practice patterns in Europe and in the USA with corresponding opinions on current and future treatments for platinum-sensitive recurrent OC.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBevacizumabEuropeFemaleHumansNeoplasm Recurrence, LocalOvarian NeoplasmsPlatinumPoly(ADP-ribose) Polymerase InhibitorsUnited StatesBevacizumabPlatinumPoly(ADP-ribose) Polymerase InhibitorsAnti-angiogenicMaintenance therapyOvarian cancerPARP inhibitorsPlatinum-sensitive

Identifiers

PMID34751835
OpenAlexW3212228511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.