Evidence map›Paper›PMID 34751804›Full record

ArticleWorld journal of surgery2022

Postoperative Stroke After Type A Aortic Dissection Repair: Hemorrhage Versus Ischemia.

Chun-Yu Lin, Chuo-Yu Lee, Hsin-Fu Lee, Meng-Yu Wu, Chi-Nan Tseng, Feng-Chun Tsai, Yu-Hsuan Lin

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Article in World journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chun-Yu LinDepartment of Medicine, College of Medicine, Chang Gung University, Taoyuan city, Taiwan.
Chuo-Yu LeeDepartment of Neurology, Mackay Memorial Hospital, Taipei city, Taiwan.
Hsin-Fu LeeDepartment of Medicine, College of Medicine, Chang Gung University, Taoyuan city, Taiwan.
Meng-Yu WuDepartment of Medicine, College of Medicine, Chang Gung University, Taoyuan city, Taiwan.
Chi-Nan TsengDepartment of Medicine, College of Medicine, Chang Gung University, Taoyuan city, Taiwan.
Feng-Chun TsaiDepartment of Medicine, College of Medicine, Chang Gung University, Taoyuan city, Taiwan.
Yu-Hsuan LinInstitute of Population Health Sciences, National Health Research Institutes, 35 Keyan Road, Zhunan Township, Miaoli County, 35053, Taiwan. yuhsuanlin@nhri.edu.tw.ORCID http://orcid.org/0000-0001-9393-3886
Chang Gung University · TWMackay Memorial Hospital · TWNational Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative stroke is a severe and potentially disabling complication following surgical intervention for acute type A aortic dissection (ATAAD). This retrospective study aims to compare the early and late outcomes between patients who had hemorrhagic and ischemic stroke after undergoing ATAAD repair surgery.

methodsBetween January 2007 and June 2020, a total of 685 consecutive patients underwent ATAAD repair at our institution. Patients who had a preoperative stroke or were unconscious at presentation were excluded from this study. Of the 656 included for analysis, 102 (15.5%) patients had a postoperative stroke confirmed by computed tomography angiography. The strokes were classified into the ischemia group (n = 83, 12.7%) and hemorrhage group (n = 19, 2.9%). Clinical features, surgical information, postoperative complications, modified Rankin Scale (mRS) scores after discharge, and 5-year cumulative survival rates were compared.

resultsDemographics, comorbidities, and presentations of ATAAD were similar between the two groups, except a higher rate of preoperative antithrombotic medication was found in the hemorrhage group. The hemorrhage group was associated with a higher complexity of aortic arch replacement, longer cardiopulmonary bypass, and aortic clamping times than the ischemia group. A higher in-hospital mortality rate (42.1% versus 20.5%; p = 0.048) and a higher median mRS score at the 3-month follow-up after discharge (6[3-6] versus 4[2-6]; p = 0.027) were found in the hemorrhage group. The hemorrhage group showed a lower 5-year cumulative survival rate (23.4% versus 57.8%; p = 0.003) compared with the ischemia group.

conclusionsPostoperative hemorrhagic stroke was associated with poorer neurological outcomes and lower survival rates than those with ischemic stroke. Patients who have complex arch replacement, long cardiopulmonary bypass and aortic clamping times are at risk for postoperative hemorrhagic stroke and should have intensive neurological surveillance for early diagnosis and treatment after ATAAD repair surgery.

Indexed as

Aortic Aneurysm, ThoracicAortic DissectionStrokeAcute DiseaseHemorrhageHumansIschemiaPostoperative ComplicationsRetrospective StudiesTreatment Outcome

Identifiers

PMID34751804
OpenAlexW3214084005

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.