ReviewJAMA2021
Cardiogenic Shock After Acute Myocardial Infarction: A Review.
Review in JAMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 206 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
206 citing papers in PubMed, 4 syntheses or guidelines pooled it, 362 citations in OpenAlex.
- [Mortality in patients with cardiogenic shock associated with the use of microaxial flow pump: a systematic review and meta-analysis].Archivos de cardiologia de Mexico · 2025Pooled it
- Early versus delayed coronary angiography in patients with out-of-hospital cardiac arrest and no ST-segment elevation: a systematic review and meta-analysis of randomized controlled trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Pooled it
- Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomized controlled trials and propensity score-matched studies.Intensive care medicine · 2024Pooled it
- Efficacy of venoarterial extracorporeal membrane oxygenation with and without intra-aortic balloon pump in adult cardiogenic shock.Frontiers in cardiovascular medicine · 2024Pooled it
- A nomogram model for predicting intramyocardial hemorrhage post-PCI based on SYNTAX score and clinical features.BMC cardiovascular disorders · 2024Trial
- Known Unknowns: Unpacking Controversies and Uncertainties in the 2025 Guidelines for Management of Acute Coronary Syndromes.Current cardiology reports · 2026Review
- Lactylation at the metabolic-epigenetic interface in cardiovascular diseases: context-dependent mechanisms and translational roadmap.Journal of advanced research · 2026Review
- Total Left Main Occlusion ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock and Delayed Sinus Node Dysfunction.The American journal of case reports · 2026Article
- Disparities in the management of cardiogenic shock complicating acute myocardial infarction: a questionnaire survey in Beijing.BMC cardiovascular disorders · 2026Article
- Admission Serum Sodium as an Early Integrative Marker of Shock Severity in Acute Myocardial Infarction-Complicated Cardiogenic Shock.Biomedicines · 2026Article
- Characteristics and In-Hospital Outcomes of Self-Transport Patients With Acute Myocardial Infarction: A Nationwide Analysis.Circulation reports · 2026Article
- Temporal Trends in Cardiogenic Shock Complicating Acute Myocardial Infarction in South Korea.Korean circulation journal · 2026Article
- Way(s) Forward for Evidence Generation in Cardiogenic Shock.Circulation. Heart failure · 2026Article
- Shock Timing in STEMI-CS: Management and Outcomes in a Resource-Limited Setting.JACC. Advances · 2026Article
- Baseline Ventricular-Arterial Coupling Modifies Left Atrial Pressure Response to Venoarterial Extracorporeal Membrane Oxygenation In Vitro.Artificial organs · 2026Article
- Timing of veno-arterial extracorporeal membrane oxygenation in cardiogenic shock: A systematic review and meta-analysis.Journal of intensive medicine · 2026Article
- Axial Flow Percutaneous Ventricular Assist Devices: Physiology, Procedural Considerations, and Clinical Applications-A State-of-the-Art Review.Structural heart : the journal of the Heart Team · 2026Review
- The Role of PoCUS in the Diagnosis and Early Monitoring of Cardiogenic Shock in the Emergency Department: A Narrative Review.Reviews in cardiovascular medicine · 2026Review
- Article
- Pressure-Adjusted Heart Rate Predicts Mortality and Resource Utilization in Cardiogenic Shock: An Analysis of the MIMIC-IV Database.Journal of cardiovascular development and disease · 2026Article
146 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
importanceCardiogenic shock affects between 40 000 and 50 000 people in the US per year and is the leading cause of in-hospital mortality following acute myocardial infarction. OBSERVATIONS: Thirty-day mortality for patients with cardiogenic shock due to myocardial infarction is approximately 40%, and 1-year mortality approaches 50%. Immediate revascularization of the infarct-related coronary artery remains the only treatment for cardiogenic shock associated with acute myocardial infarction supported by randomized clinical trials. The Percutaneous Coronary Intervention Strategies with Acute Myocardial Infarction and Cardiogenic Shock (CULPRIT-SHOCK) clinical trial demonstrated a reduction in the primary outcome of 30-day death or kidney replacement therapy; 158 of 344 patients (45.9%) in the culprit lesion revascularization-only group compared with 189 of 341 patients (55.4%) in the multivessel percutaneous coronary intervention group (relative risk, 0.83 [95% CI, 0.71-0.96]; P = .01). Despite a lack of randomized trials demonstrating benefit, percutaneous mechanical circulatory support devices are frequently used to manage cardiogenic shock following acute myocardial infarction. CONCLUSIONS AND RELEVANCE: Cardiogenic shock occurs in up to 10% of patients immediately following acute myocardial infarction and is associated with mortality rates of nearly 40% at 30 days and 50% at 1 year. Current evidence and clinical practice guidelines support immediate revascularization of the infarct-related coronary artery as the primary therapy for cardiogenic shock following acute myocardial infarction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.