Evidence map›Paper›PMID 34751689›Full record

ArticleLab on a chip2021

A frugal microfluidic pump.

Apresio K Fajrial, Adam Vega, Gazendra Shakya, Xiaoyun Ding

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Microfluidic pumps for cell sorting.Biomicrofluidics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Apresio K FajrialPaul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, 80309, USA. Xiaoyun.Ding@colorado.edu.ORCID 0000-0001-8946-6648
Adam VegaPaul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, 80309, USA. Xiaoyun.Ding@colorado.edu.
Gazendra ShakyaPaul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, 80309, USA. Xiaoyun.Ding@colorado.edu.ORCID 0000-0001-7747-2012
Xiaoyun DingPaul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, 80309, USA. Xiaoyun.Ding@colorado.edu.ORCID 0000-0003-4252-9335
University of Colorado Boulder · US

Funding

Cell membrane disruption and recovery for intracellular deliveryR35GM142817 · NIGMS · UNIVERSITY OF COLORADO · PI DING, XIAOYUN · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM142817NIGMS NIH HHS RGM142817A
6 · The paper itself

Abstract

Manipulation of fluid flow is paramount for microfluidic device operation. Conventional microfluidic pumps are often expensive, bulky, complicated, and not amenable in limited resource settings. Here, we introduce a Fully self-sufficient, RobUst, Gravity-Assisted, Low-cost (FRUGAL) microfluidic pump. The pump consists of a syringe, a syringe holder and loading masses. The system is easy to assemble, inexpensive, portable, and electrical power-free. Inside the syringe, the fluid is driven by the pressure from the weight of the loading masses. During operation, the exerted pressure is dynamically controllable and stable for hours. These features are useful for optimization of microfluidics assays and dynamic temporal studies. We demonstrate the application of this system to control the formation of water-in-oil droplet emulsion. Benefitting from its simplicity and versatility, the frugal microfluidic pump will enable global adoption of microfluidic technology in chemistry and biomedical applications, especially in limited resource environments.

Indexed as

Lab-On-A-Chip DevicesMicrofluidicsElectricityGravitationSyringes

Identifiers

PMID34751689
PMCPMC8805482
OpenAlexW3209923813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.