Evidence map›Paper›PMID 34751663›Full record

ArticleJMIR mHealth and uHealth2021

Gait and Axial Spondyloarthritis: Comparative Gait Analysis Study Using Foot-Worn Inertial Sensors.

Julie Soulard, Jacques Vaillant, Athan Baillet, Philippe Gaudin, Nicolas Vuillerme

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03761212 (Gait Parameters as Predictors of Functional and Activity Scores in Ankylosing Spondylitis), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03761212 completednot on this map

Gait Parameters as Predictors of Functional and Activity Scores in Ankylosing Spondylitis : the FoLoMI Study

TypeobservationalSponsorUniversity Hospital, GrenobleRan2018 to 2022Enrolled90ConditionsAnkylosing Spondylitis
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Julie SoulardUniversity Grenoble Alpes, AGEIS, La Tronche, France.ORCID 0000-0001-8138-1447
Jacques VaillantUniversity Grenoble Alpes, AGEIS, La Tronche, France.ORCID 0000-0001-5288-7086
Athan BailletUniversity Grenoble Alpes, CNRS, Grenoble Alpes University Hospital, Grenoble INP, TIMC-IMAG UMR5525, Grenoble, France.ORCID 0000-0001-6006-2519
Philippe GaudinUniversity Grenoble Alpes, CNRS, Grenoble Alpes University Hospital, Grenoble INP, TIMC-IMAG UMR5525, Grenoble, France.ORCID 0000-0002-7864-280X
Nicolas VuillermeUniversity Grenoble Alpes, AGEIS, La Tronche, France.ORCID 0000-0003-3773-393X
Institut polytechnique de Grenoble · FRUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAxial spondyloarthritis (axSpA) can lead to spinal mobility restrictions associated with restricted lower limb ranges of motion, thoracic kyphosis, spinopelvic ankylosis, or decrease in muscle strength. It is well known that these factors can have consequences on spatiotemporal gait parameters during walking. However, no study has assessed spatiotemporal gait parameters in patients with axSpA. Divergent results have been obtained in the studies assessing spatiotemporal gait parameters in ankylosing spondylitis, a subgroup of axSpA, which could be partly explained by self-reported pain intensity scores at time of assessment. Inertial measurement units (IMUs) are increasingly popular and may facilitate gait assessment in clinical practice.

objectiveThis study compared spatiotemporal gait parameters assessed with foot-worn IMUs in patients with axSpA and matched healthy individuals without and with pain intensity score as a covariate.

methodsA total of 30 patients with axSpA and 30 age- and sex-matched healthy controls performed a 10-m walk test at comfortable speed. Various spatiotemporal gait parameters were computed from foot-worn inertial sensors including gait speed in ms

resultsAge, height, and weight were not significantly different between groups. Self-reported pain intensity was significantly higher in patients with axSpA than healthy controls (P<.001). Independent sample t tests indicated that patients with axSpA presented lower gait speed (P<.001) and cadence (P=.004), shorter stride length (P<.001) and swing time (P<.001), and longer double support time (P<.001) and stance time (P<.001) than healthy controls. When using pain intensity as a covariate, spatiotemporal gait parameters were still significant with patients with axSpA exhibiting lower gait speed (P<.001), shorter stride length (P=.001) and swing time (P<.001), and longer double support time (P<.001) and stance time (P<.001) than matched healthy controls. Interestingly, there were no longer statistically significant between-group differences observed for the cadence (P=.17).

conclusionsGait was significantly altered in patients with axSpA with reduced speed, cadence, stride length, and swing time and increased double support and stance time. Taken together, these changes in spatiotemporal gait parameters could be interpreted as the adoption of a so-called cautious gait pattern in patients with axSpA. Among factors that may influence gait in patients with axSpA, patient self-reported pain intensity could play a role. Finally, IMUs allowed computation of spatiotemporal gait parameters and are usable to assess gait in patients with axSpA in clinical routine.

trial registrationClinicalTrials.gov NCT03761212; https://clinicaltrials.gov/ct2/show/NCT03761212. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1007/s00296-019-04396-4.

Indexed as

Axial SpondyloarthritisGait AnalysisFootGaitHumansWalkingankylosing spondylitisdigital healthgaitlocomotionmobilitypainsensorsspatiotemporalspondyloarthritis

Identifiers

PMID34751663
PMCPMC8663701
OpenAlexW3211472253

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.