ArticleBioresource technology2022
Process optimisation for production and recovery of succinic acid using xylose-rich hydrolysates by Actinobacillus succinogenes.
Article in Bioresource technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 57 citations in OpenAlex.
- Formate-driven in situ COBiotechnology for biofuels and bioproducts · 2026Article
- Recovery Yield and Defective Product Rate in a Bio-Based Amino Acid Crystallization Process.ACS omega · 2026Article
- Efficient bioconversion of deinked paper sludge into valuable biobased succinic acid by engineered3 Biotech · 2025Article
- Evolution-assisted engineering ofBiodesign research · 2025Article
- Recent advances in bio-based production of top platform chemical, succinic acid: an alternative to conventional chemistry.Biotechnology for biofuels and bioproducts · 2024Review
- Mutation breeding of high-stress resistant strains for succinic acid production from corn straw.Applied microbiology and biotechnology · 2024Article
- Succinic acid - A run-through of the latest perspectives of production from renewable biomass.Heliyon · 2024Review
- An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis.Nature communications · 2023Article
- Citrate Synthase Overexpression ofACS omega · 2023Article
- Development of Hypertolerant Strain ofACS sustainable chemistry & engineering · 2022Article
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Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Succinic acid (SA) is a top platform chemical obtainable from biomass. The current study evaluated the potential of Actinobacillus succinogenes for SA production using xylose-rich hemicellulosic fractions of two important lignocellulosic feedstocks, olive pits (OP) and sugarcane bagasse (SCB) and the results were compared with pure xylose. Initial experiments were conducted in shake flask followed by batch and fed-batch cultivation in bioreactor. Further separation of SA from the fermented broth was carried out by adapting direct crystallisation method. During fed-batch culture, maximum SA titers of 36.7, 33.6, and 28.7 g/L was achieved on pure xylose, OP and SCB hydrolysates, respectively, with same conversion yield of 0.27 g/g. The recovery yield of SA accumulated on pure xylose, OP and SCB hydrolysates was 79.1, 76.5, and 75.2%, respectively. The results obtained are of substantial value and pave the way for development of sustainable SA biomanufacturing in an integrated biorefinery.
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