Evidence map›Paper›PMID 34751153›Full record

ReviewNeuroImage2021

The diversity and specificity of functional connectivity across spatial and temporal scales.

Tatiana A Engel, Marieke L Schölvinck, Christopher M Lewis

Abstract readReview
In one paragraph

Review in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Revisiting alpha-theta cross-frequency dynamics during working memory.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Distinct Cortical Populations Drive Multisensory Modulation of Segregated Auditory Sources.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Fast-local and slow-global neural ensembles in the mouse brain.Network neuroscience (Cambridge, Mass.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tatiana A EngelCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States. Electronic address: engel@cshl.edu.
Marieke L SchölvinckErnst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany. Electronic address: marieke.scholvinck@esi-frankfurt.de.
Christopher M LewisLaboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zürich, Zürich 8057, Switzerland. Electronic address: lewis@hifo.uzh.ch.

Funding

Multiscale computational frameworks for integrating large-scale cortical dynamics, connectivity, and behaviorRF1DA055666 · NIDA · PRINCETON UNIVERSITY · PI ENGEL, TATIANA · 2021 to 2021
$1.3M
Discovering dynamic computations from large-scale neural activity recordingsR01EB026949 · NIBIB · COLD SPRING HARBOR LABORATORY · PI ENGEL, TATIANA · 2018 to 2020
$1.3M
European Research Council 670757NIBIB NIH HHS R01 EB026949NIDA NIH HHS RF1 DA055666
6 · The paper itself

Abstract

Macroscopic neuroimaging modalities in humans have revealed the organization of brain-wide activity into distributed functional networks that re-organize according to behavioral demands. However, the inherent coarse-graining of macroscopic measurements conceals the diversity and specificity in responses and connectivity of many individual neurons contained in each local region. New invasive approaches in animals enable recording and manipulating neural activity at meso- and microscale resolution, with cell-type specificity and temporal precision down to milliseconds. Determining how brain-wide activity patterns emerge from interactions across spatial and temporal scales will allow us to identify the key circuit mechanisms contributing to global brain states and how the dynamic activity of these states enables adaptive behavior.

Indexed as

ConnectomeAnimalsFunctional NeuroimagingHumansNeural Pathways

Identifiers

PMID34751153
PMCPMC9531047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.