Evidence map›Paper›PMID 34751011›Full record

ArticleJournal of Korean medical science2021

Prevalence of SARS-CoV-2 Antibody in 2,935 Healthcare Workers at 6 Major Hospitals, Daegu, Korea.

Yu Kyung Kim, Dohsik Minn, Do Young Song, Chae Hoon Lee, Nam Hee Ryoo, Chang-Ho Jeon, Kyung Eun Song, Jang Soo Suh, Soon Hee Chang

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Yu Kyung Kim *Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-4699-8502
Dohsik Minn *Department of Diagnostic Immunology, Seegene Medical Foundation, Seoul, Korea.ORCID https://orcid.org/0000-0002-5794-9714
Do Young SongDepartment of Laboratory Medicine, Daegu Fatima Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-5474-8327
Chae Hoon LeeDepartment of Laboratory Medicine, Yeungnam University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0001-7722-9004
Nam Hee RyooDepartment of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0001-8383-709X
Chang-Ho JeonDepartment of Laboratory Medicine, Daegu Catholic University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-7450-7117
Kyung Eun SongDepartment of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0003-1628-4741
Jang Soo SuhDepartment of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-9684-2020
Soon Hee ChangDepartment of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea. marta10@hanmail.net.ORCID https://orcid.org/0000-0003-3031-2200
Kyungpook National University · KRDaegu Catholic University Medical Center · KRDaegu Fatima Hospital · KRKeimyung University · KRKyungpook National University Hospital · KRYeungnam University College

Funding

Seegene Medical Foundation
6 · The paper itself

Abstract

backgroundIn Korea, the first community outbreak of coronavirus disease 2019 (COVID-19) occurred in Daegu on February 18, 2020. This study was performed to investigate the prevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibodies in healthcare workers (HCWs) at 6 major hospitals in Daegu.

methodsBlood specimens of 2,935 HCWs at 6 major hospitals in Daegu from January 2021 to February 2021 were collected. Every specimen was tested for antibody against SARS-CoV-2 using both Elecsys Anti-SARS-CoV-2 electrochemiluminescence immunoassay (Roche Diagnostics, Rotkreuz, Switzerland) and R-FIND COVID-19 IgG/M/A enzyme-linked immunosorbent assay kit (SG medical Inc., Seoul, Korea) as screening tests. If 1 or more of these screening test results was positive, 2 additional antibody tests were performed using Abbott Anti-SARS-CoV-2 IgG assay (Abbott, Abbott Park, IL, USA) and cPass SARS-CoV-2 Neutralization Antibody Detection Kit (GenScript USA Inc., Piscataway, NJ, USA). If 2 or more of the total 4 test results were positive, it was determined as positive for the antibody against SARS-CoV-2.

resultsAccording to the criteria of SARS-CoV-2 antibody positivity determination, 12 subjects were determined as positive. The overall positive rate of the SARS-CoV-2 antibody was 0.41% (12/2,935). Of the 12 subjects determined as positive, 7 were diagnosed with COVID-19, and the remaining 5 were nondiagnosed cases of COVID-19.

conclusionIn early 2021, the overall seroprevalence of SARS-CoV-2 antibody among HCW located in Daegu was 0.41%, and 0.17% excluding COVID-19 confirmed subjects. These results were not particularly high compared with the general public and were much lower than HCWs in other countries.

Indexed as

AdultAgedAntibodies, NeutralizingAntibodies, ViralAntibody SpecificityCOVID-19Enzyme-Linked Immunosorbent AssayFemaleHealth PersonnelHospitalsHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MMaleMiddle AgedAntibodies, NeutralizingAntibodies, ViralImmunoglobulin AImmunoglobulin GImmunoglobulin MCOVID-19Healthcare WorkerNeutralizing AntibodySARS-CoV-2 Antibody

Identifiers

PMID34751011
PMCPMC8575762
OpenAlexW3209745422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.