Evidence map›Paper›PMID 34750974›Full record

ArticleInfluenza and other respiratory viruses2022

Using capture-recapture methods to estimate influenza hospitalization incidence rates.

Goundappa K Balasubramani, Mary Patricia Nowalk, Lloyd G Clarke, Klancie Dauer, Fernanda Silveira, Donald B Middleton, Mohamed Yassin, Richard K Zimmerman

Abstract read
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Article in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Goundappa K BalasubramaniDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7221-1825
Mary Patricia NowalkDepartment of Family Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-1702-2690
Lloyd G ClarkeDepartment of Pharmacy, Division of Infectious Diseases/Pharmacy Department, UPMC Health System, Pittsburgh, Pennsylvania, USA.
Klancie DauerDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Fernanda SilveiraDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Donald B MiddletonDepartment of Medical Education, UPMC St. Margaret, Pittsburgh, Pennsylvania, USA.
Mohamed YassinInfection Control Department, UPMC Mercy, Pittsburgh, Pennsylvania, USA.
Richard K ZimmermanDepartment of Family Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Flu vaccine effectiveness in thosehospitalized in a large diverse health systemU01IP000969 · IP · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZIMMERMAN, RICHARD K · 2015 to 2019
$4.5M
ACL HHS U01IP001035NCATS NIH HHS UL1 TR001857NCIRD CDC HHS U01 IP000969NCIRD CDC HHS U01 IP001035
6 · The paper itself

Abstract

backgroundAccurate population estimates of disease incidence and burden are needed to set appropriate public health policy. The capture-recapture (C-R) method combines data from multiple sources to provide better estimates than is possible using single sources.

methodsData were derived from clinical virology test results and from an influenza vaccine effectiveness study from seasons 2016-2017 to 2018-2019. The Petersen C-R method was used to estimate the population size of influenza cases; these estimates were then used to calculate adult influenza hospitalization burden using a Centers for Disease Control and Prevention (CDC) multiplier method.

resultsOver all seasons, 343 influenza cases were reported in the clinical database, and 313 in the research database. Fifty-nine cases (17%) reported in the clinical database were not captured in the research database, and 29 (9%) cases in the research database were not captured in the clinical database. Influenza hospitalizations were higher among vaccinated (58%) than the unvaccinated (35%) in the current season and were similar among unvaccinated (51%) and vaccinated (49%) in the previous year. Completeness of the influenza hospitalization capture was estimated to be 76%. The incidence rates for influenza hospitalizations varied by age and season and averaged 307-309 cases/100,000 adult population annually.

conclusionUsing C-R methods with more than one database, along with a multiplier method with adjustments improves the population estimates of influenza disease burden compared with relying on a single-data source.

Indexed as

Influenza, HumanInfluenza VaccinesAdultHospitalizationHumansIncidenceSeasonsInfluenza Vaccinescapture-recapturehospitalizationinfluenzainfluenza burdeninfluenza incidence

Identifiers

PMID34750974
PMCPMC8818814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.