Evidence map›Paper›PMID 34750951›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2022

Association between remnant cholesterol and arterial stiffness: A secondary analysis based on a cross-sectional study.

Zhenwei Wang, Min Li, Jing Xie, Jing Gong, Naifeng Liu

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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  15. The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhenwei WangDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.ORCID 0000-0001-7524-135X
Min LiDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Jing XieCollege of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Jing GongDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Naifeng LiuDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zhongda Hospital Southeast University · CNChina Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between conventional lipid parameters and arterial stiffness (AS) has been verified by previous studies. However, it remains unknown whether non-conventional lipid parameters have certain predictive effect on AS represented by brachial-ankle pulse wave velocity (baPWV). Therefore, the study was to explore the relationship between remnant cholesterol (RC) and other non-conventional lipid parameters and AS in the general population free from cardiovascular disease. The study included 912 participants aged 24-84 years from a medical health checkup center of Murakami Memorial Hospital. Logistic regression analysis and receiver operating characteristic (ROC) curves were used to examine the association between non-conventional lipid parameters and AS. The results showed that compared with non-AS group, the AS group had higher RC, non-high-density lipoprotein cholesterol (Non-HDL-C), atherogenic index of plasma (AIP), lipoprotein combine index (LCI), atherosclerosis index (AI), triglycerides/HDL-C (TG/HDL-C), Castelli's risk index I (CRI-I) and Castelli's risk index II (CRI-II). Then, the authors divided participants into two groups by the optimal cutoff point of 23.6 of RC determined by Youden index. The baPWV was significantly higher in higher RC group compared with lower RC group, and RC was positively correlated with baPWV. Multivariate Logistic regression analysis showed that, regarding lower RC as reference, higher RC was independently associated with higher risk of AS, independent of other risk factors (OR = 1.794, 95% CI: 1.267-2.539, p = .001). The area under the curve of AS predicted by RC was higher than that of other non-conventional lipid parameters (almost all p < .05). The findings indicated that increased RC was a significant predictor of AS.

Indexed as

HypertensionVascular StiffnessAdultAgedAged, 80 and overAnkle Brachial IndexCholesterolCross-Sectional StudiesHumansMiddle AgedPulse Wave AnalysisRisk FactorsYoung AdultCholesterol

Identifiers

PMID34750951
PMCPMC8783357
OpenAlexW3211870534

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.