Evidence map›Paper›PMID 34750853›Full record

ArticleJournal of veterinary internal medicine2021

Prevalence of sudden cardiac death in dogs with atrial fibrillation.

Kieran Borgeat, Matthew Pack, Jo Harris, Alex Laver, Joonbum Seo, Omri Belachsen, Joshua Hannabuss, Julie Todd, Luca Ferasin, Jessie Rose Payne

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evaluation of Galectin-3 in Dogs with Atrial Fibrillation.Animals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Prevalence of sudden cardiac death in dogs with atrial fibrillation.Journal of veterinary internal medicine · 2021
    Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Kieran BorgeatSmall Animal Hospital, Langford Vets, University of Bristol, Bristol, United Kingdom.ORCID https://orcid.org/0000-0001-9199-4941
Matthew PackSmall Animal Hospital, Langford Vets, University of Bristol, Bristol, United Kingdom.
Jo HarrisHeartVets, Dursley, United Kingdom.
Alex LaverHeartVets, Dursley, United Kingdom.
Joonbum SeoQueen Mother Hospital for Animals, Royal Veterinary College, London, United Kingdom.ORCID https://orcid.org/0000-0002-8215-1237
Omri BelachsenSouthern Counties Veterinary Specialists, Ringwood, United Kingdom.
Joshua HannabussQueen Mother Hospital for Animals, Royal Veterinary College, London, United Kingdom.
Julie ToddPride Veterinary Centre, Derby, United Kingdom.
Luca FerasinSpecialist Veterinary Cardiology Consultancy, Alton, United Kingdom.ORCID https://orcid.org/0000-0002-6898-7900
Jessie Rose PayneSmall Animal Hospital, Langford Vets, University of Bristol, Bristol, United Kingdom.
University of Bristol · GBRoyal Veterinary College · GBValve (United States) · US21c Consultancy (United Kingdom) · GBSouthern Oncology Specialists · USUniversity of Derby · GB

Funding

The Langford Trust
6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is associated with increased risk of sudden cardiac death (SCD) in humans, independent of secondary risk factors such as thrombogenic disorders. In dogs, SCD is described in a number of heart diseases, but an association between AF and SCD is unreported. HYPOTHESIS: (a) A higher proportion of dogs with AF will experience SCD, and (b) SCD will be associated with complex ventricular arrhythmias. ANIMALS: One-hundred forty-two dogs with AF, and 127 dogs without AF.

methodsRetrospective, multicenter, case-control study. Dogs included in the AF group were compared to a control group of dogs in sinus rhythm, matched for echocardiographic diagnosis. Descriptive statistics were used to identify proportions of each group suffering SCD, compared using chi-squared testing. Risk factors for SCD in dogs with AF were evaluated at the univariable and multivariable level using binary logistic regression. Significance was P < .05.

resultsA significantly higher proportion of dogs with AF suffered SCD than dogs in the control group (14.8% vs 5.5%; P = .01). Younger age at diagnosis, larger left atrial size, and a history of syncope all were independent predictors of SCD in dogs with AF (χ CONCLUSIONS AND CLINICAL IMPORTANCE: Atrial fibrillation was associated with a higher prevalence of SCD in dogs. A history of syncope may be a useful predictor of SCD risk.

Indexed as

Atrial FibrillationDog DiseasesAnimalsCase-Control StudiesDeath, Sudden, CardiacDogsPrevalenceRetrospective StudiesRisk FactorscardiologyechocardiographyHolter analysisventricular arrhythmia

Identifiers

PMID34750853
PMCPMC8692199
OpenAlexW3212581999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.