Evidence map›Paper›PMID 34750815›Full record

ArticleJournal of the American Geriatrics Society2022

"Real-world" eligibility for aducanumab depends on clinical setting and patients' journey.

Alessandro Padovani, Salvatore Caratozzolo, Luca Rozzini, Andrea Pilotto, Alberto Benussi, Gioacchino Tedeschi

Abstract readLetter
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Eligibility for donanemab trial in a population-based study of cognitive aging.The journal of prevention of Alzheimer's disease · 2025
    Trial
  2. Observational
  3. Italian intersocietal recommendations for restructuring the diagnostic-therapeutic pathway for the implementation and appropriate use of anti-amyloid monoclonal antibodies in Alzheimer's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  4. Patient eligibility for amyloid-targeting immunotherapies in Alzheimer's disease.The journal of prevention of Alzheimer's disease · 2025
    Article
  5. Article
  6. Validation and convergent validity of the Boston cognitive assessment (BOCA) in an Italian population: a comparative study with the Montreal cognitive assessment (MoCA) in Alzheimer's disease spectrum.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro PadovaniNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.ORCID 0000-0002-0119-3639
Salvatore CaratozzoloNeurology Unit, Department of Neurological and Vision Sciences, ASST Spedali Civili, Brescia, Italy.
Luca RozziniNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Andrea PilottoNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.ORCID 0000-0003-2029-6606
Alberto BenussiNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Gioacchino TedeschiNeurology Unit, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease ProgressionEligibility DeterminationAgedAlzheimer DiseaseAntibodies, Monoclonal, HumanizedCognitive DysfunctionDrug ApprovalHumansUnited StatesUnited States Food and Drug AdministrationaducanumabAntibodies, Monoclonal, Humanized

Identifiers

PMID34750815
PMCPMC9298825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.