Evidence map›Paper›PMID 34750499›Full record

ArticleNPJ digital medicine2021

Wearable sensor derived decompensation index for continuous remote monitoring of COVID-19 diagnosed patients.

Dylan M Richards, MacKenzie J Tweardy, Steven R Steinhubl, David W Chestek, Terry L Vanden Hoek, Karen A Larimer, Stephan W Wegerich

Abstract read
In one paragraph

Article in NPJ digital medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. A Call to Expand the Scope of Digital Phenotyping.Journal of medical Internet research · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dylan M RichardsphysIQ Inc., 200 W Jackson Blvd Suite 550, Chicago, IL, USA.
MacKenzie J TweardyphysIQ Inc., 200 W Jackson Blvd Suite 550, Chicago, IL, USA.
Steven R SteinhublphysIQ Inc., 200 W Jackson Blvd Suite 550, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-9256-7914
David W ChestekUniversity of Illinois Health, Chicago, IL, USA.
Terry L Vanden HoekUniversity of Illinois Health, Chicago, IL, USA.
Karen A LarimerphysIQ Inc., 200 W Jackson Blvd Suite 550, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0023-618X
Stephan W WegerichphysIQ Inc., 200 W Jackson Blvd Suite 550, Chicago, IL, USA. stephan.wegerich@physiq.com.ORCID http://orcid.org/0000-0002-0306-7265

Funding

DIGITAL HEALTH SOLUTIONS FOR COVID-19: PERSONALIZED ANALYTICS WEARABLE BIOSENSOR PLATFORM FOR EARLY DETECTION OF COVID-19 DECOMPENSATION75N91020C00040 · NCI · VGBIO, INC. · PI LARIMER, KAREN · 2020 to 2021
$6.6M
NCI NIH HHS 75N91020C00040
6 · The paper itself

Abstract

The COVID-19 pandemic has accelerated the adoption of innovative healthcare methods, including remote patient monitoring. In the setting of limited healthcare resources, outpatient management of individuals newly diagnosed with COVID-19 was commonly implemented, some taking advantage of various personal health technologies, but only rarely using a multi-parameter chest-patch for continuous monitoring. Here we describe the development and validation of a COVID-19 decompensation index (CDI) model based on chest patch-derived continuous sensor data to predict COVID-19 hospitalizations in outpatient-managed COVID-19 positive individuals, achieving an overall AUC of the ROC Curve of 0.84 on 308 event negative participants, and 22 event positive participants, out of an overall study cohort of 400 participants. We retrospectively compare the performance of CDI to standard of care modalities, finding that the machine learning model outperforms the standard of care modalities in terms of both numbers of events identified and with a lower false alarm rate. While only a pilot phase study, the CDI represents a promising application of machine learning within a continuous remote patient monitoring system.

Identifiers

PMID34750499
PMCPMC8576003

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.