ArticleScientific reports2021
Developing an in-vivo physiological porcine model of inducing acute atraumatic compartment syndrome towards a non-invasive diagnosis using shear wave elastography.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Ultrasound-derived tibia-fascia angle for noninvasive assessment of intracompartmental pressure in tibial plateau fractures.PloS one · 2026Observational
- Shear wave elastography for noninvasive assessment of intracompartmental pressure in tibial plateau fractures: a cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- Researcher's guide to preclinical animal models of acute extremity compartment syndrome.Trauma surgery & acute care open · 2025Review
- [Diagnostics of acute compartment syndrome : Current gold standard and the state of science of noninvasive assessment methods].Chirurgie (Heidelberg, Germany) · 2024Review
- Establishment and pathophysiological evaluation of a novel model of acute compartment syndrome in rats.BMC musculoskeletal disorders · 2024Article
- Comparison of intracompartment pressure changes in tibial plateau fractures and controlled people: A pilot study.PloS one · 2024Article
- Venous congestion affects neuromuscular changes in pigs in terms of muscle electrical activity and muscle stiffness.PloS one · 2023Article
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5 authors at 3 institutions in 1 country.
Funding
Abstract
Compartment syndrome (CS) is a pathological event caused by elevated intracompartmental pressure (ICP); however, changes from the onset of inducing atraumatic CS remained unclear. The study aimed to investigate the physiological changes in a newly developed in vivo porcine acute atraumatic CS model. CS was induced by ischemia-reperfusion injury in the left hind leg of fourteen pigs divided into an echogenicity group (EG) and a shear wave elastography group (SEG). Echogenicity was measured in EG, and shear elastic modulus (SEM) was measured in SEG seven times before, at the onset of inducing CS, and every 30 min after the onset over eight hours. Simultaneously, ICP, blood pressure, and muscle perfusion pressure (MPP) were also measured in both groups. Our results indicate that SEM of the experimental leg in SEG significantly increased as CS developed compared to the control leg (p = 0.027), but no statistical difference in the echogenicity in EG was found between the experimental leg and control leg. There were also significant correlations between SEM and ICP (p < 0.001) and ICP and MPP (p < 0.001). Our method and findings can be a basis to develop a non-invasive diagnostic tool using a shear wave elastography for atraumatic CS.
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