Evidence map›Paper›PMID 34750356›Full record

ArticleTranslational psychiatry2021

Synaptic Zn

Juan L Gomez, Jordi Bonaventura, Jacqueline Keighron, Kelsey M Wright, Dondre L Marable, Lionel A Rodriguez, Sherry Lam, Meghan L Carlton, Randall J Ellis, Chloe J Jordan and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. An emerging role for synaptic ZnPharmacology & therapeutics · 2026
    Review
  2. Acid-sensing ion channels and their role in controlling pain in the post-operative stage.International journal of physiology, pathophysiology and pharmacology · 2026
    Review
  3. Article
  4. Genes · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Juan L GomezBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Jordi BonaventuraBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.ORCID http://orcid.org/0000-0002-4745-0151
Jacqueline KeighronMedication Development Program, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Kelsey M WrightBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.ORCID http://orcid.org/0000-0002-5625-585X
Dondre L MarableBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Lionel A RodriguezBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Sherry LamBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Meghan L CarltonBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Randall J EllisBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Chloe J JordanAddiction Biology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.ORCID http://orcid.org/0000-0002-1843-227X
Guo-Hua BiAddiction Biology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Oscar SolisBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Marco PignatelliDepartment of Psychiatry and Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St Louis, MO, 63110, USA.
Michael J BannonDepartment of Pharmacology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.ORCID http://orcid.org/0000-0002-9887-4309
Zheng-Xiong XiAddiction Biology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Gianluigi TandaMedication Development Program, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.ORCID http://orcid.org/0000-0001-9526-9878
Michael MichaelidesBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA. mike.michaelides@nih.gov.ORCID http://orcid.org/0000-0003-0398-4917
National Institute on Drug Abuse · USTaylor Family Institute for Innovative Psychiatric ResearchWayne State University · US

Funding

Investigation On The Behavior And Related Neuro-Electrochemistry Of Potential Medications For The Treatment Of Substance Use Disorders.ZIADA000611 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI TANDA, GIANLUIGI · 2016 to 2025
$16.0M
6 · The paper itself

Abstract

Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn

Indexed as

CocaineDopamineAnimalsCorpus StriatumDopamine Plasma Membrane Transport ProteinsMiceNucleus AccumbensSynaptic TransmissionZincCocaineDopamineDopamine Plasma Membrane Transport ProteinsZinc

Identifiers

PMID34750356
PMCPMC8575899
OpenAlexW3211921280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.