ArticleProceedings of the National Academy of Sciences of the United States of America2021
Air pollution interacts with genetic risk to influence cortical networks implicated in depression.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- PMiScience · 2026Review
- Long-Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A genome-wide interaction study of thyroid-stimulating hormone levels and particulate matter exposure among Koreans.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026Article
- Article
- Large language model powered knowledge graph construction for mental health exploration.Nature communications · 2025Article
- Beyond single targets: leveraging degeneracy in sodium channels for osteoarthritis analgesia.Pain reports · 2025Article
- The independent role of fine particulate matter and genetic liability on cognition in older adults.Annals of general psychiatry · 2025Article
- Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution.Critical reviews in toxicology · 2024Review
- How does the macroenvironment influence brain and behaviour-a review of current status and future perspectives.Molecular psychiatry · 2024Review
- Interactive effect of air pollution and genetic risk of depression on processing speed by resting-state functional connectivity of occipitoparietal network.BMC medicine · 2024Article
- Nature and human well-being: The olfactory pathway.Science advances · 2024Review
- Mendelian randomization study supports the causal effects of air pollution on longevity via multiple age-related diseases.npj aging · 2023Article
- How does the macroenvironment influence brain and behaviour - a review of current status and future perspectives.medRxiv : the preprint server for health sciences · 2023Article
- Scorpion venom heat-resistant peptide alleviates mitochondrial dynamics imbalance induced by PMToxicology research · 2023Article
- Genetic susceptibility and lifestyle modify the association of long-term air pollution exposure on major depressive disorder: a prospective study in UK Biobank.BMC medicine · 2023Article
- Overview of particulate air pollution and human health in China: Evidence, challenges, and opportunities.Innovation (Cambridge (Mass.)) · 2022Review
- Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?Translational psychiatry · 2022Review
- Unsuppressed Striatal Activity and Genetic Risk for Schizophrenia Associated With Individual Cognitive Performance Under Social Competition.Schizophrenia bulletin · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Air pollution is a reversible cause of significant global mortality and morbidity. Epidemiological evidence suggests associations between air pollution exposure and impaired cognition and increased risk for major depressive disorders. However, the neural bases of these associations have been unclear. Here, in healthy human subjects exposed to relatively high air pollution and controlling for socioeconomic, genomic, and other confounders, we examine across multiple levels of brain network function the extent to which particulate matter (PM
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.