ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2021
Diagnostic performance of chest radiography measurements for the assessment of cardiac chamber enlargement.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
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5 citing papers in PubMed, 12 citations in OpenAlex.
- Comparative Evaluation of Feature Selection Strategies for ICU Mortality Prediction Using Chest Radiographic, Radiomic, and Demographic Features.Diagnostics (Basel, Switzerland) · 2026Article
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- Quality Assessment of Plain Chest X-Rays of the Expatriates in Jordan: Multi-Centres Study.Risk management and healthcare policy · 2025Article
- Correction to "Diagnostic performance of chest radiography measurements for the assessment of cardiac chamber enlargement".CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Is cardiothoracic point-of-care ultrasonography the future of heart failure diagnosis?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe cardiothoracic ratio (CTR) is commonly assessed on chest radiography for detection of cardiac chamber enlargement, but the traditional cutpoint of 0.5 has low specificity. We sought to evaluate the diagnostic accuracy of new measurement techniques for the detection of cardiac enlargement on chest radiographs.
methodsWe obtained retrospective cross-sectional data on consecutive patients who underwent both chest radiography and cardiac magnetic resonance imaging (MRI) within a 14-day interval between 2006 and 2016 at a large academic hospital network. We established the presence of cardiac chamber enlargement using cardiac MRI as the reference standard. We evaluated the diagnostic performance of different techniques for measuring heart size and CTR on frontal chest radiographs.
resultsOf 152 patients included, 81 (53%) were men and the mean age was 52 years. Maximum heart diameter had the highest area under the receiver operating characteristic curve for detection of cardiac enlargement (0.827, 95% confidence interval 0.760-0.894). In the subgroup of posteroanterior chest radiography studies (
interpretationA traditional CTR cutpoint of 0.5 has limited diagnostic value. Simple heart diameter measurements have higher diagnostic performance measures than CTR.
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