Evidence map›Paper›PMID 34749716›Full record

ArticleBMC women's health2021

Prevalence, risk factors, and management practices of primary dysmenorrhea among young females.

Samar Karout, Lama Soubra, Deema Rahme, Lina Karout, Hani M J Khojah, Rania Itani

4 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05664048 nacompletednot on this map

Effects of Dry Heat Application on Menstrual Symptoms and Pain: A Randomized Controlled Trial

TypeinterventionalSponsorManisa Celal Bayar UniversityRan2019 to 2019Enrolled65ConditionsReproductive HealthArmsDry heat application
NCT05771753 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparison of Core Stabilization and Dynamic Stretching Exercises on Symptoms Severity and Quality of Life in Primary Dysmenorrhea

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2023Enrolled32ConditionsPrimary DysmenorrheaArmsStretching Exercises, Dynamic core stabilizing exercises
NCT06146569 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Transcutaneous Vagus Nerve Stimulation (taVNS) in Individuals With Primary Dysmenorrhea: A Randomized Controlled Study

TypeinterventionalSponsorArtvin Coruh UniversityRan2023 to 2024Enrolled50ConditionsDysmenorrhea Primary, PainArmsTranscutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
NCT06233786 phase3unknown statusnot on this mapstarted 2024, after this paper: background citation

Effectiveness of Non-invasive Neuromodulation in Primary Dysmenhorrea: A Randomized Clinical Trial

TypeinterventionalSponsorNaiara Benítez AramburuRan2024 to 2024Enrolled30ConditionsPrimary DysmenorrheaArmsTranscutaneous Electrical Nerve Stimulation (TENS)
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 146 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Samar KaroutPharmacy Practice Department, Faculty of Pharmacy, Beirut Arab University, Riad El Solh, P.O. Box 11-5020, Beirut, 1107 2809, Lebanon.
Lama SoubraPharmacology and Therapeutics Department, Faculty of Pharmacy, Beirut Arab University, Riad El Solh, P.O. Box 11-5020, Beirut, 1107 2809, Lebanon.
Deema RahmePharmacy Practice Department, Faculty of Pharmacy, Beirut Arab University, Riad El Solh, P.O. Box 11-5020, Beirut, 1107 2809, Lebanon.
Lina KaroutDepartment of Radiology, American University of Beirut Medical Center, Riad El-Solh, P.O. Box 11-0236, Beirut, 1107 2020, Lebanon.
Hani M J KhojahDepartment of Clinical and Hospital Pharmacy, College of Pharmacy, Taibah University, Madinah, Kingdom of Saudi Arabia.
Rania ItaniPharmacy Practice Department, Faculty of Pharmacy, Beirut Arab University, Riad El Solh, P.O. Box 11-5020, Beirut, 1107 2809, Lebanon. r.itani@bau.edu.lb.
Beirut Arab University · LBAmerican University of Beirut · LBTaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary dysmenorrhea (PD) is one of the most common gynecological conditions among young females, which has a significant negative impact on health-related quality of life and productivity. Despite its high prevalence, the evidence is limited regarding the management-seeking practices and its perceived effectiveness among females with PD.

methodsThis is a cross-sectional study conducted among 550 female students in six universities across Lebanon. The prevalence of PD, associated risk factors, and management-seeking practices were assessed using a self-administered questionnaire.

resultsThe prevalence of PD was 80.9%. Most of the females with PD described their menstrual pain as moderate (56%) to severe (34.6%), which significantly affected their daily activities and studying ability (P < 0.001). The major risk factors associated with PD included heavy menstrual flow (adjusted odds ratio [AOR] = 10.28), family history of PD (AOR = 2.52), history of weight loss attempt (AOR = 2.05), and medical specialization (AOR = 1.663). Only 36.9% of females with PD sought formal medical advice. Most dysmenorrheic females (76.4%) received medications for the management of PD, and remarkably none of them took hormonal contraceptives. Drugs commonly used for PD were mefenamic acid (26.2%), ibuprofen (25%), and paracetamol (11.5%), which were administered when the pain started (58.2%). All medications were significantly effective in reducing the pain score (P = 0.001), and most NSAIDs were more potent than paracetamol in managing PD (P = 0.001). However, no significant difference in adverse effects among medications was revealed. Moreover, no superiority of any individual NSAID for pain relief was established. Nevertheless, mefenamic acid was associated with the lowest risk of abdominal pain (OR: 0.03, P = 0.005) and the highest risk of flank pain (OR = 12, P = 0.02).

conclusionsSuboptimal management of PD is practiced among university students in Lebanon. Therefore, health care providers should educate dysmenorrheic females to optimize the self-management support of PD. Furthermore, future research is required to investigate females' misconceptions about hormonal contraceptives in the management of PD, aiming to raise awareness and correct misconceptions.

Indexed as

DysmenorrheaQuality of LifeCross-Sectional StudiesFemaleHumansPrevalenceRisk FactorsLebanonManagement-seeking practicesMenstrual painNon-steroidal anti-inflammatory drugsPrevalencePrimary dysmenorrheaRisk factors

Identifiers

PMID34749716
PMCPMC8576974
OpenAlexW3214305794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.