ArticleBMC oral health2021
Number of teeth is associated with all-cause and disease-specific mortality.
Article in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of edentulism on community-dwelling adults in low-income, middle-income and high-income countries: a systematic review.BMJ open · 2024Pooled it
- Candidate loci shared among periodontal disease, diabetes and bone density.Frontiers in endocrinology · 2022Pooled it
- Association Between Toothbrushing Habits and Mucosal Healing in Japanese Patients with Ulcerative Colitis.Digestive diseases and sciences · 2026Article
- Article
- Dietary patterns of U.S. older adults and their associations with diet quality, health and food insecurity.Public health nutrition · 2026Article
- Oral Function, Frailty and Mortality in Older Adults: Evidence from the Chilean National Health Survey 2016-2017.International journal of environmental research and public health · 2026Article
- Association of healthy lifestyle with tooth count among adults aged 20 years and above: a cross-sectional study.BMC oral health · 2026Article
- Strong Heart, Strong Smile: Tooth Loss and Incidence of CVD in American Indian Populations.Community dentistry and oral epidemiology · 2026Article
- Divergent effects of oral health and genetic risk: competing risks of dementia and mortality.Innovation in aging · 2026Article
- Sugary Snack and Drink Consumption and Tooth Retention Among Residents with Disabilities in Thai Foster Homes: A Cross-Sectional Study.Clinical, cosmetic and investigational dentistry · 2026Article
- Dental Disease as a Clinical Marker for Coronary Artery Disease Severity: A Narrative Review of Current Evidence and Mechanisms.Medicina (Kaunas, Lithuania) · 2025Review
- Prechemoradiotherapy number of natural teeth as a prognostic factor in patients with locally advanced nasopharyngeal cancer: A retrospective observational study.The Journal of international medical research · 2025Observational
- Association of tooth loss with circadian syndrome in US adults: the mediated role of systemic inflammation.Clinical oral investigations · 2025Article
- Cost-Effectiveness Analysis of Oral Health Care Package of Services within a Comprehensive PhilHealth Benefit Package.Acta medica Philippina · 2025Article
- Tooth loss and mortality risk: the mediating role of hs-CRP in a Chinese cohort.Frontiers in oral health · 2025Article
- Tooth loss trajectories and their association with all-cause mortality among older Chinese adults.Frontiers in oral health · 2025Article
- The Number of Remaining Teeth-A Predictability Factor for a Certain Type of Cardiovascular Condition in a Group of Hospitalized Individuals.Journal of personalized medicine · 2024Article
- Association of oral health with all-cause and cause-specific mortality in older Chinese adults: A 14-year follow-up of the Guangzhou Biobank Cohort study.Journal of global health · 2024Article
- Article
- Self-reported oral health is associated with systemic health outcomes and all-cause mortality.Journal of the American Dental Association (1939) · 2024Article
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Abstract
backgroundTooth loss has been shown to correlate with multiple systemic comorbidities. However, the associations between the number of remaining natural teeth (NoT) and all-cause mortality have not been explored extensively. We aimed to investigate whether having fewer NoT imposes a higher risk in mortality. We tested such hypotheses using three groups of NoT (20-28,10-19, and 0-9), edentulism and without functional dentition (NoT < 19).
methodsThe National Health and Nutrition Examination Survey in the United States (NHANES) (1999-2014) conducted dental examinations and provided linkage of mortality data. NHANES participants aged 20 years and older, without missing information of dental examination, age, gender, race, education, income, body-mass-index, smoking, physical activities, and existing systemic conditions [hypertension, total cardiovascular disease, diabetes, and stroke (N = 33,071; death = 3978), or with femoral neck bone mineral density measurement (N = 13,131; death = 1091)] were analyzed. Cox proportional hazard survival analyses were used to investigate risks of all-cause, heart disease, diabetes and cancer mortality associated with NoT in 3 groups, edentulism, or without functional dentition.
resultsParticipants having fewer number of teeth had higher all-cause and disease-specific mortality. In fully-adjusted models, participants with NoT0-9 had the highest hazard ratio (HR) for all-cause mortality [HR(95%CI) = 1.46(1.25-1.71); p < .001], mortality from heart diseases [HR(95%CI) = 1.92(1.33-2.77); p < .001], from diabetes [HR(95%CI) = 1.67(1.05-2.66); p = 0.03], or cancer-related mortality [HR(95%CI) = 1.80(1.34-2.43); p < .001]. Risks for all-cause mortality were also higher among the edentulous [HR(95%CI) = 1.35(1.17-1.57); p < .001] or those without functional dentition [HR(95%CI) = 1.34(1.17-1.55); p < .001].
conclusionsHaving fewer NoT were associated with higher risks for all-cause mortality. More research is needed to explore possible biological implications and validate our findings.
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