ArticleBMC cardiovascular disorders2021
Estimated plasma volume status (ePVS) is a predictor for acute myocardial infarction in-hospital mortality: analysis based on MIMIC-III database.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 18 citations in OpenAlex.
- Estimated plasma volume status and the risk of 30-day mortality among patients with traumatic brain injury: analysis from the MIMIC-IV database.Frontiers in neurology · 2026Article
- Association of estimated plasma volume status with 30-day mortality risk in patients with cardiogenic shock: an analysis based on MIMIC-IV database.BMC cardiovascular disorders · 2025Article
- Association between estimated plasma volume status and the risk of 30-day mortality in patients with severe acute pancreatitis: a retrospective study based on the MIMIC-IV database.BMC gastroenterology · 2025Article
- High-level ePVS was accompanied by an increase in kidney transplant failure risk: analysis based on the MIMIC-IV database.Frontiers in immunology · 2025Article
- Estimated Plasma Volume Status and the Risk of in-Hospital Mortality Among Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care Unit: Retrospective Cohort Study from the eICU Collaborative Research Database.International journal of chronic obstructive pulmonary disease · 2025Article
- Estimated plasma volume status as a prognostic indicator in myocardial infarction and heart failure: insights from the MIMIC-IV database.Frontiers in cardiovascular medicine · 2025Article
- Article
- Estimated plasma volume status as a simple and accessible predictor of 28-day mortality in septic shock: insights from a retrospective study of the MIMIC-IV database.Frontiers in medicine · 2024Article
- Estimated plasma volume status in COVID-19 patients and its relation to comorbidities and clinical outcomes.Journal of thrombosis and thrombolysis · 2024Article
- Letter to the editor regarding 'Discordance between estimated and measured changes in plasma volume among patients with acute heart failure'.ESC heart failure · 2022Article
- Prediction of unplanned 30-day readmission for ICU patients with heart failure.BMC medical informatics and decision making · 2022Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEstimated plasma volume status (ePVS) has been reported that associated with poor prognosis in heart failure patients. However, no researchinvestigated the association of ePVS and prognosis in patients with acute myocardial infarction (AMI). Therefore, we aimed to determine the association between ePVS and in-hospital mortality in AMI patients. METHODS AND
resultsWe extracted AMI patients data from MIMIC-III database. A generalized additive model and logistic regression model were used to demonstrate the association between ePVS levels and in-hospital mortality in AMI patients. Kaplan-Meier survival analysis was used to pooled the in-hospital mortality between the various group. ROC curve analysis were used to assessed the discrimination of ePVS for predicting in-hospital mortality. 1534 eligible subjects (1004 males and 530 females) with an average age of 67.36 ± 0.36 years old were included in our study finally. 136 patients (73 males and 63 females) died in hospital, with the prevalence of in-hospital mortality was 8.9%. The result of the Kaplan-Meier analysis showed that the high-ePVS group (ePVS ≥ 5.28 mL/g) had significant lower survival possibility in-hospital admission compared with the low-ePVS group (ePVS < 5.28 mL/g). In the unadjusted model, high-level of ePVS was associated with higher OR (1.09; 95% CI 1.06-1.12; P < 0.001) compared with low-level of ePVS. After adjusted the vital signs data, laboratory data, and treatment, high-level of ePVS were also associated with increased OR of in-hospital mortality, 1.06 (95% CI 1.03-1.09; P < 0.001), 1.05 (95% CI 1.01-1.08; P = 0.009), 1.04 (95% CI 1.01-1.07; P = 0.023), respectively. The ROC curve indicated that ePVS has acceptable discrimination for predicting in-hospital mortality. The AUC value was found to be 0.667 (95% CI 0.653-0.681).
conclusionHigher ePVS values, calculated simply from Duarte's formula (based on hemoglobin/hematocrit) was associated with poor prognosis in AMI patients. EPVS is a predictor for predicting in-hospital mortality of AMI, and could help refine risk stratification.
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