Evidence map›Paper›PMID 34749631›Full record

ArticleBMC bioinformatics2021

Application of artificial intelligence ensemble learning model in early prediction of atrial fibrillation.

Cai Wu, Maxwell Hwang, Tian-Hsiang Huang, Yen-Ming J Chen, Yiu-Jen Chang, Tsung-Han Ho, Jian Huang, Kao-Shing Hwang, Wen-Hsien Ho

Open access · goldAbstract read
In one paragraph

Article in BMC bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Cai WuDepartment of Hematology, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, No. 1, Shangcheng Road, Yiwu, Zhejiang, China.
Maxwell HwangDepartment of Colorectal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88, Jiefang Road, Hangzhou, Zhejiang, China.
Tian-Hsiang HuangCenter for Big Data Research, Kaohsiung Medical University, No.100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Yen-Ming J ChenDepartment of Logistics Management, National Kaohsiung University of Science and Technology, No.1, University Road, Kaohsiung, 824, Taiwan.
Yiu-Jen ChangDepartment of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, No.100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan.
Tsung-Han HoDepartment of Engineering Science, National Cheng Kung University, No.1, University Road, Tainan, 701, Taiwan.
Jian HuangDepartment of Hematology, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, No. 1, Shangcheng Road, Yiwu, Zhejiang, China.
Kao-Shing HwangDepartment of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, No.100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan. hwang@g-mail.nsysu.edu.tw.
Wen-Hsien HoDepartment of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, No.100, Shin-Chuan 1st Road, Kaohsiung, 807, Taiwan. whho@kmu.edu.tw.ORCID http://orcid.org/0000-0001-6194-0563
Kaohsiung Medical University · TWZhejiang University · CNNational Cheng Kung University · TWNational Kaohsiung University of Science and TechnologyNational Sun Yat-sen University · TWSecond Affiliated Hospital of Zhejiang University · CN

Funding

Ministry of Education Intelligent Manufacturing Research CenterMinistry of Science and Technology, Taiwan MOST 108-2221-E-037-007Ministry of Science and Technology, Taiwan MOST 109-2221-E-037-005National Sun Yat-Sen University-Kaohsiung Medical University NSYSUKMU 108-P006
6 · The paper itself

Abstract

backgroundAtrial fibrillation is a paroxysmal heart disease without any obvious symptoms for most people during the onset. The electrocardiogram (ECG) at the time other than the onset of this disease is not significantly different from that of normal people, which makes it difficult to detect and diagnose. However, if atrial fibrillation is not detected and treated early, it tends to worsen the condition and increase the possibility of stroke. In this paper, P-wave morphology parameters and heart rate variability feature parameters were simultaneously extracted from the ECG. A total of 31 parameters were used as input variables to perform the modeling of artificial intelligence ensemble learning model.

resultsThis paper applied three artificial intelligence ensemble learning methods, namely Bagging ensemble learning method, AdaBoost ensemble learning method, and Stacking ensemble learning method. The prediction results of these three artificial intelligence ensemble learning methods were compared. As a result of the comparison, the Stacking ensemble learning method combined with various models finally obtained the best prediction effect with the accuracy of 92%, sensitivity of 88%, specificity of 96%, positive predictive value of 95.7%, negative predictive value of 88.9%, F1 score of 0.9231 and area under receiver operating characteristic curve value of 0.911.

conclusionIn feature extraction, this paper combined P-wave morphology parameters and heart rate variability parameters as input parameters for model training, and validated the value of the proposed parameters combination for the improvement of the model's predicting effect. In the calculation of the P-wave morphology parameters, the hybrid Taguchi-genetic algorithm was used to obtain more accurate Gaussian function fitting parameters. The prediction model was trained using the Stacking ensemble learning method, so that the model accuracy had better results, which can further improve the early prediction of atrial fibrillation.

Indexed as

Atrial FibrillationAlgorithmsArtificial IntelligenceElectrocardiographyHumansMachine LearningROC CurveArtificial intelligenceAtrial fibrillationElectrocardiogramEnsemble learning

Identifiers

PMID34749631
PMCPMC8576960
OpenAlexW3212232251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.