ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022
Country differences in transmissibility, age distribution and case-fatality of SARS-CoV-2: a global ecological analysis.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Machine Learning Used in Communicable Disease Control: A Scoping Review.Public health reviews · 2026Pooled it
- Speaking Different Languages Impacts Size-Resolved Exhaled Breath Aerosol Particle Emission.Environment & health (Washington, D.C.) · 2025Article
- Beyond schistosomiasis: unraveling co-infections and altered immunity.Clinical microbiology reviews · 2024Review
- Analyzing the worldwide progression of COVID-19 cases and deaths using nonlinear mixed-effects model.PloS one · 2024Article
- Factors associated with adverse outcomes among patients hospitalized at a COVID-19 treatment center in Herat, Afghanistan.PLOS global public health · 2023Article
- Geoepidemiological perspective on COVID-19 pandemic review, an insight into the global impact.Frontiers in public health · 2023Review
- The impact of age structure and vaccine prioritization on COVID-19 in West Africa.Infectious Disease Modelling · 2022Article
- The notable global heterogeneity in the distribution of COVID-19 cases and the association with pre-existing parasitic diseases.PLoS neglected tropical diseases · 2022Article
- Characterization and determinant factors of critical illness and in-hospital mortality of COVID-19 patients: A retrospective cohort of 1,792 patients in Kenya.Biosafety and health · 2022Article
- The Contributions of Pandemic Severity, Government Stringency, Cultural Values and Internet Usage to Post-traumatic Stress Disorder During the COVID-19 Pandemic: An Analysis of Data From 35 Countries.Frontiers in sociology · 2022Article
- Evaluating COVID-19 decision-making in a humanitarian setting: The case study of Somalia.PLOS global public health · 2022Article
- Date of introduction and epidemiologic patterns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Mogadishu, Somalia: estimates from transmission modelling of satellite-based excess mortality data in 2020.Wellcome open research · 2021Article
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Authors and funding
5 authors.
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Abstract
Objectives The first COVID-19 pandemic waves in many low-income countries appeared milder than initially forecasted. We conducted a country-level ecological study to describe patterns in key SARS-CoV-2 outcomes by country and region and explore associations with potential explanatory factors, including population age structure and prior exposure to endemic parasitic infections. Methods We collected publicly available data and compared them using standardisation techniques. We then explored the association between exposures and outcomes using random forest and linear regression. We adjusted for potential confounders and plausible effect modifications. Results While mean time-varying reproduction number was highest in the European and Americas regions, median age of death was lower in the Africa region, with a broadly similar case-fatality ratio. Population age was strongly associated with mean (β=0.01, 95% CI, 0.005, 0.011) and median age of cases (β=-0.40, 95% CI, -0.53, -0.26) and deaths (β= 0.40, 95% CI, 0.17, 0.62). Conclusions Population age seems an important country-level factor explaining both transmissibility and age distribution of observed cases and deaths. Endemic infections seem unlikely, from this analysis, to be key drivers of the variation in observed epidemic trends. Our study was limited by the availability of outcome data and its causally uncertain ecological design.
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