Evidence map›Paper›PMID 34748992›Full record

ReviewDrug discovery today2022

Artificial intelligence for the discovery of novel antimicrobial agents for emerging infectious diseases.

Adam Bess, Frej Berglind, Supratik Mukhopadhyay, Michal Brylinski, Nicholas Griggs, Tiffany Cho, Chris Galliano, Kishor M Wasan

Open access · greenAbstract readReview
In one paragraph

Review in Drug discovery today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. AI-Powered Microscopic Diagnostic Techniques forJournal of dentistry (Shiraz, Iran) · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. A Chronicle Review ofIndian journal of microbiology · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Adam BessDepartment of Computer Sciences, Louisiana State University, Baton Rouge, LA, USA. Electronic address: bess@deepdrug.ai.
Frej BerglindDepartment of Mathematics, Louisiana State University, Baton Rouge, LA, USA.
Supratik MukhopadhyayDepartment of Computer Sciences, Louisiana State University, Baton Rouge, LA, USA.
Michal BrylinskiDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA.
Nicholas GriggsTrinity Consultants Inc., Mountain View, CA, USA.
Tiffany ChoTrinity Consultants Inc., Mountain View, CA, USA.
Chris GallianoSkymount Medical US Inc, New Orleans, LA, USA.
Kishor M WasanSkymount Medical US Inc, New Orleans, LA, USA; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address: Kishor.Wasan@ubc.ca.
Louisiana State University · USUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for effective drugs to treat new and existing diseases is a laborious one requiring a large investment of capital, resources, and time. The coronavirus 2019 (COVID-19) pandemic has been a painful reminder of the lack of development of new antimicrobial agents to treat emerging infectious diseases. Artificial intelligence (AI) and other in silico techniques can drive a more efficient, cost-friendly approach to drug discovery by helping move potential candidates with better clinical tolerance forward in the pipeline. Several research teams have developed successful AI platforms for hit identification, lead generation, and lead optimization. In this review, we investigate the technologies at the forefront of spearheading an AI revolution in drug discovery and pharmaceutical sciences.

Indexed as

Artificial IntelligenceCOVID-19 Drug TreatmentSARS-CoV-2AnimalsAnti-Infective AgentsCommunicable Diseases, EmergingDrug DiscoveryHumansAnti-Infective AgentsAntimicrobial agentsArtificial intelligenceCOVID-19Infectious diseases

Identifiers

PMID34748992
PMCPMC8570449
OpenAlexW3213493452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.