Evidence map›Paper›PMID 34748955›Full record

ArticleComplementary therapies in medicine2021

A naturopathic treatment approach for mild and moderate COVID-19: A retrospective chart review.

Melissa S Barber, Richard Barrett, Ryan D Bradley, Erin Walker

Open access · goldAbstract read
In one paragraph

Article in Complementary therapies in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melissa S BarberNational University of Natural Medicine, Helfgott Research Institute, 2220 SW 1st Ave, Portland, OR, United States. Electronic address: drmelissabarber@gmail.com.
Richard BarrettNational University of Natural Medicine, Helfgott Research Institute, 2220 SW 1st Ave, Portland, OR, United States. Electronic address: rbarrett@nunm.edu.
Ryan D BradleyNational University of Natural Medicine, Helfgott Research Institute, 2220 SW 1st Ave, Portland, OR, United States. Electronic address: rbradley@nunm.edu.
Erin WalkerCanby Clinic, 452 NW 1st Ave, Canby, OR, United States. Electronic address: drwalker@canbyclinic.com.
National University of Natural Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe coronavirus disease 2019 (COVID-19) pandemic has led to significant morbidity and mortality. Although COVID-19 vaccination is available, therapeutic options are still needed. The goal of the present manuscript is to report on a treatment strategy used in a naturopathic medical practice for mild and moderate COVID-19.

designA retrospective chart review was conducted of 30 consecutive patients diagnosed with mild and moderate COVID-19 who were provided multi-nutrient, herbal, and probiotic treatment in a rural, out-patient, naturopathic primary care setting. MAIN OUTCOMES MEASURES: The primary outcome was treatment safety; secondary outcomes included changes in symptoms, progression to severe COVID-19, incidence of long COVID, and recovery time.

resultsNo side effects or adverse events were reported from treatment and all patients experienced resolution of symptoms presumed to be associated with COVID-19 infection. One patient who had been ill for 28 days prior to presentation was hospitalized. Five patients had an illness duration of more than one month. Time to treatment was correlated with duration of illness post-treatment (r = 0.63, p < 0.001) and more symptoms at presentation was correlated with a longer duration of illness (r = 0.52, p < 0.01).

conclusionsIn this retrospective chart review, a multi-nutrient, herbal, and probiotic therapeutic approach for mild and moderate COVID-19 appeared to be well-tolerated. Delay in seeking treatment after symptom onset, as well as more symptoms at presentation, were correlated with a longer duration of illness. This treatment strategy may have clinical benefit, warranting prospective clinical trials with confirmed COVID-19 cases.

Indexed as

COVID-19COVID-19 VaccinesHumansPost-Acute COVID-19 SyndromeProspective StudiesRetrospective StudiesSARS-CoV-2COVID-19 VaccinesCase reportsComplementary therapiesCOVID-19Herbal medicineImmune systemIntegrative medicineIntravenous infusionsMineralsNaturopathic medicineNutrition therapyOrthomolecular therapyPhytotherapySARS-CoV-2Vitamins

Identifiers

PMID34748955
PMCPMC8570825
OpenAlexW3213281814

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.