Evidence map›Paper›PMID 34748576›Full record

ArticlePloS one2021

Feasibility of oral HIV self-testing in female sex workers in Gaborone, Botswana.

Emily Shava, Laura M Bogart, Kutlo Manyake, Charlotte Mdluli, Kamogelo Maribe, Neo Monnapula, Bornapate Nkomo, Mosepele Mosepele, Sikhulile Moyo, Mompati Mmalane and 3 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Emily ShavaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.ORCID 0000-0001-9288-7881
Laura M BogartRAND Corporation, Santa Monica, California, United States of America.
Kutlo ManyakeBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Charlotte MdluliBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Kamogelo MaribeNkaikela Youth Group, Gaborone, Botswana.
Neo MonnapulaNkaikela Youth Group, Gaborone, Botswana.
Bornapate NkomoMinistry of Health & Wellness, Gaborone, Botswana.
Mosepele MosepeleBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Sikhulile MoyoBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Mompati MmalaneBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Till BärnighausenHarvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Joseph MakhemaBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Shahin LockmanBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Mentoring in Patient-Oriented HIV Research in the Era of Universal ARTK24AI131928 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAHIN LOCKMAN · 2017 to 2026
$1.9M
Innovative HIV Testing Strategy for Middle-to-Upper Income Men in a Resource Limited SettingR21TW011069 · FIC · UNIVERSITY OF BOTSWANA · PI BOGART, LAURA M, MOSEPELE, MOSEPELE · 2018 to 2019
$232k
FIC NIH HHS R21 TW011069NIAID NIH HHS K24 AI131928NIAID NIH HHS P30 AI060354NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundOral HIV self-testing (HIVST) may be useful for increasing testing in persons at elevated risk of acquiring HIV.

methodsWe conducted a pilot study to evaluate the feasibility (defined by uptake) of HIVST among FSW in Gaborone, Botswana. FSW age 18 years and above were recruited through a non-governmental organization serving FSW. FSW with unknown or negative HIV status at screening performed HIVST in the study clinic following brief training. FSW testing HIV-negative were each given two test kits to take home: one kit to perform unassisted HIVST and another to share with others. Feasibility (use) of HIVST (and sharing of test kits with others) was assessed in these women at a study visit four months later.

resultsTwo hundred FSW were screened. Their average age was 34 years (range 18-59), and 115 (58%) were HIV-positive. Eighty-five (42%) tested HIV-negative at entry and were eligible to take part in the HIVST pilot study. All 85 (100%) agreed to take home HIVST kits. Sixty-nine (81%) of these 85 participants had a follow-up visit, 56 (81%) of whom reported performing HIVST at a mean of three and half months after the initial visit. All 56 participants who performed HIVST reported negative HIVST results. Fifty (73%) of the 69 participants who took HIVST kits home shared them with others. Of the 50 women sharing HIVST kits, 25 (50%) shared with their non-client partners, 15 with a family member, 8 with friends, and 3 with a client. One participant did not test herself but shared both her test kits. Most participants 53/56 (95%) found oral HIVST very easy to use whilst 3/56 (5%) felt it was fairly easy.

conclusionOral HIVST is feasible among FSW in Gaborone, Botswana. The majority of FSW used the HIVST kits themselves and also shared extra HIVST kits with other individuals.

Indexed as

Feasibility StudiesHIV InfectionsSelf-TestingSex WorkersAdolescentAdultBotswanaFemaleHumansMiddle AgedPilot ProjectsYoung Adult

Identifiers

PMID34748576
PMCPMC8575243

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.