ArticleAnalytical and bioanalytical chemistry2022
Comparison of LC-ESI, DART, and ASAP for the analysis of oligomers migration from biopolymer food packaging materials in food (simulants).
Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Green Analytical Workflows: Recent Advances in Sample Preparation and Instrumental Analysis of Food Contact Materials.Molecules (Basel, Switzerland) · 2026Review
- Evaluating the chemical safety of bio-based and biodegradable food packaging materials through non-targeted LC-HRMS analysis and in vitro bioassays.Analytical and bioanalytical chemistry · 2026Article
- A Systematic Review: Migration of Chemical Compounds from Plastic Material Containers in Food and Pharmaceutical Fields.Journal of xenobiotics · 2025Review
- Biochemical Modification of Poly-Vinyl-Alcohol-Based Bioplastics withInternational journal of molecular sciences · 2025Article
- Article
- Screening and Relative Quantification of Migration from Novel Thermoplastic Starch and PBAT Blend Packaging.Foods (Basel, Switzerland) · 2025Article
- Recent and emerging food packaging alternatives: Chemical safety risks, current regulations, and analytical challenges.Comprehensive reviews in food science and food safety · 2024Review
- Article
- Applications of ambient ionization mass spectrometry in 2021: An annual review.Analytical science advances · 2022Review
- Degradation strategies for structural characterization of insoluble synthetic polymers by mass spectrometry.Mass spectrometry reviewsReview
- Rapid, Sensitive, and Versatile: A 5-Year Perspective on Applications of Ambient Ionization Mass Spectrometry in Bioanalytical Science.Mass spectrometry reviewsReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Biopolymers based on polylactic acid (PLA) and starch have numerous advantages, such as coming from renewable sources or being compostable, though they can have deficiencies in mechanical properties, and for this reason, polyester resins are occasionally added to them in order to improve their properties. In this work, migration from a PLA sample and from another starch-based biopolymer to three different food simulants was studied. Attention was focused on the determination of oligomers. The analysis was first performed by ultraperformance liquid chromatography quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS), which allowed the identification of the oligomers present in migration. Then, the samples were analyzed by two ambient desorption/ionization techniques directly coupled to mass spectrometry (ADI), direct analysis in real-time coupled to standardized voltage and pressure (DART-MS) and atmospheric pressure solids analysis probe (ASAP-MS). These methodologies were able to detect simultaneously the main oligomers migrants and their adducts in a very rapid and effective way. Nineteen different polyester oligomers, fourteen linear and five cyclic, composed of different combinations of adipic acid [AA], propylene glycol [PG], dipropylene glycol [DPG], 2,2-dibutyl-1,3-propanediol [DBPG], or isobutanol [i-BuOH] were detected in migration samples from PLA. In migration samples from starch-based biopolymer, fourteen oligomers from poly(butylene adipate co-terephthalate) polyester (PBAT) were identified, twelve cyclic and two linear. The results from ADI techniques showed that they are a very promising alternative tool to assess the safety and legal compliance of food packaging materials.
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Registered trials
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