Observational studyEuropean journal of physical and rehabilitation medicine2022
Predictors of changes in 6-min walking distance following pulmonary rehabilitation in COPD patients: a retrospective cohort analysis.
Observational study in European journal of physical and rehabilitation medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Efficacy of inpatient pulmonary rehabilitation in elderly patients with acute exacerbation of COPD: randomised controlled trial study.Irish journal of medical science · 2026Article
- Effectiveness of repeated pulmonary rehabilitation in patients with chronic obstructive pulmonary disease.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2026Article
- On the effectiveness of rehabilitative exercise training in COPD: why does contractile muscle fatigue matter?ERJ open research · 2025Article
- Effects of Physical Exercise on Walking Distance and Functional Limitations in Patients with Chronic Dyspnea.Medicina (Kaunas, Lithuania) · 2025Article
- Prognostic Factors for Responders of Home-Based Pulmonary Rehabilitation-Secondary Analysis of a Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
backgroundPulmonary rehabilitation (PR) is fundamental in chronic obstructive pulmonary disease (COPD) management but not all patients may show functional benefits from PR.
aimThe aim of this study was to identify predictors of non-response in functional capacity to PR.
designObservational study.
settingInpatient pulmonary rehabilitation center. POPULATION: COPD patients.
methodsThis single center study is a retrospective analysis of data in COPD patients admitted to a PR center between January 2012 and December 2017. Post-PR change in 6-min walking distance (6MWD) was used to determine the functional response to PR. Patients characteristics and pre-PR 6-min walking test responses were analyzed to determine factors associated with post-PR changes in 6MWD.
resultsData from 835 patients were analyzed as well as a subgroup of 190 patients with additional variables available. Eighty percent of the patients showed clinically significant 6MWD improvement post-PR. The predictors of 6MWD response to PR were age, pre-PR 6MWD, pre-PR end-of-test dyspnea and long-term oxygen therapy. Older patients, longer pre-PR 6MWD, higher pre-PR end-of-test dyspnea score and the use of oxygen supplementation were associated with lesser post-PR 6MWD improvement.
conclusionsThis study identified four important clinical variables predicting a lack of 6MWD response to PR. CLINICAL REHABILITATION IMPACT: Patients with such clinical characteristics may require specific PR modalities to improve their functional benefit.
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