Evidence map›Paper›PMID 34747579›Full record

SynthesisEuropean journal of physical and rehabilitation medicine2022

Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review.

Monica Sicari, Maria Longhi, Giulia D'Angelo, Valentina Boetto, Andrea Lavorato, Lorella Cocchini, Maurizio Beatrici, Bruno Battiston, Diego Garbossa, Giuseppe Massazza and 1 more

Registry-linked trialOpen access · greenAbstract readCase ReportsSystematic Review
In one paragraph

Synthesis in European journal of physical and rehabilitation medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06303427 (Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation on Range of Motion, Muscle Strength, and Motor Function in ERB's Palsy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06303427 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation on Range of Motion, Muscle Strength, and Motor Function in ERB's Palsy

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled34ConditionsErb's PalsyArmsModified constraint-induced movement therapy, Electrical stimulation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Monica SicariDepartment of Neurorehabilitation, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy.
Maria LonghiUnit of Rehabilitation Medicine, Department of Neuroscience, University Hospital of Modena, Modena, Italy - longhi.maria@aou.mo.it.
Giulia D'AngeloDivision of Physical Medicine and Rehabilitation, ASLTO3, Turin, Italy.
Valentina BoettoDepartment of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Andrea LavoratoUnit of Neurosurgery, Department of Neuroscience "Rita Levi Montalcini, " University of Turin, Turin, Italy.
Lorella CocchiniDepartment of Neurorehabilitation, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy.
Maurizio BeatriciDepartment of Neurorehabilitation, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy.
Bruno BattistonUnit of Hand and Upper Limb Surgery, Department of Orthopedics and Traumatology, Orthopedic and Trauma Center, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy.
Diego GarbossaUnit of Neurosurgery, Department of Neuroscience "Rita Levi Montalcini, " University of Turin, Turin, Italy.
Giuseppe MassazzaDivision of Physical Medicine and Rehabilitation, Department of Surgical Sciences, University of Turin, Turin, Italy.
Paolo TitoloUnit of Hand and Upper Limb Surgery, Department of Orthopedics and Traumatology, Orthopedic and Trauma Center, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy.
Fondazione Ricerca Molinette · ITUniversity of Turin · ITUniversity of Modena and Reggio Emilia · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObstetric brachial plexus palsy (OBPP) is a flaccid paralysis occurring in the upper limb during birth. The OBPP includes mild lesions with complete spontaneous recovery and severe injuries with no regain of arm function. Among the most promising rehabilitation treatments aimed at improving upper extremity motor activities in individuals with neurological dysfunctions, there is the modified constraint-induced movement therapy (mCIMT). The aim of this systematic review is to assess and synthesize the critical aspects of the use of mCIMT in children with OBPP. EVIDENCE ACQUISITION: This systematic review has been carried out according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis). A comprehensive search of the literature was conducted using PubMed, MEDLINE and Evidence Based Medicine Reviews, databases. We enclosed experimental and original articles, case reports and book chapters. Four articles were finally included. EVIDENCE SYNTHESIS: One case report tested the feasibility of mCIMT to encourage use of the affected arm in a child with Erb-Duchenne palsy and documented the clinical changes observed. A case series had the purpose to determine if mCIMT in combination with botulinum toxin (BTX-A) improved arm function in 2 children with OBPP. A cohort study compared the use of mCIMT in 19 OBPP and 18 unilateral Cerebral Palsy. A prospective single-blind RCT described mCIMT versus conventional therapy in a group of 39 children with OBPP.

conclusionsThis systematic review on the use of mCIMT in children with OBPP shows that there is unanimous agreement that a program should last 2 weeks at least. However, there is no scientific evidence supporting a single common mCIMT protocol in the management of OBPP because of a considerable heterogeneity. Further high methodological studies regarding the application of mCIMT for OBPP and based on larger patients' sample should have the potential to optimize the appropriateness of care provided to infants with OBPP and, therefore, their quality of life.

Indexed as

Brachial PlexusBrachial Plexus NeuropathiesChildCohort StudiesHumansInfantParalysisProspective StudiesQuality of LifeSingle-Blind MethodTreatment Outcome

Identifiers

PMID34747579
PMCPMC9980490
OpenAlexW3211763617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.