Evidence map›Paper›PMID 34747381›Full record

ArticleActa bio-medica : Atenei Parmensis2021

Hypertensive crisis and pulmonary edema following rituximab-induced anaphylaxis.

Stylian Brili, Evangelia Bei, Nikolas G Kounis, Christina Chrysohoou, Christos-Konstantinos Antoniou, Flora Kontopidou, Laura Bonfanti, Gianfranco Cervellin, Dimitrios Tousoulis Tousoulis, Constantinos Tsioufis

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In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Stylian BriliUniversity of Athens, Greece. stlbrili@gmail.com.
Evangelia BeiUniversity of Athens, Greece. evelinabei89@gmail.com.
Nikolas G KounisUniversity of Patras, Greece. ngkounis@otonet.gr.
Christina ChrysohoouUniversity of Athens, Greece. chrysohoou@usa.net.
Christos-Konstantinos AntoniouUniversity of Athens, Greece. ckantoniou@hotmail.gr.
Flora KontopidouUniversity of Athens, Greece. florakont@med.uoa.gr.
Laura BonfantiEmergency Department, Hospital of Sassuolo, Modena, Italy. l.bonfanti@ospedalesassuolo.it.
Gianfranco CervellinAcademy of Emergency Medicine and Care, Pavia, Italy. gianfranco.cervellin@gmail.com.
Dimitrios Tousoulis TousoulisUniversity of Athens, Greece. drtousoulis@hotmail.com.
Constantinos TsioufisUniversity of Athens, Greece. ktsioufis@gmail.com.
National and Kapodistrian University of Athens · GRUniversity of West Attica · GRAcademy of Emergency Medicine and Care · ITAthens State University · USAthens University of Economics and Business · GRCTO Hospital · ITUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rituximab is a monoclonal antibody against the protein CD20. Various lymphomas as well as non-malignant immune disorders are treated with this antibody. Hypersensitivity reactions associated with the use of rituximab include urticaria, hypotension, chest tightness, vomiting, oxygen desaturation and bronchospasm. A very uncommon case of hypertensive crisis and pulmonary edema following rituximab-induced hypersensitivity reaction in an 80-year-old man receiving rituximab for non-Hodgkin lymphoma is reported. Anaphylaxis manifesting as coronary vasospasm following drug treatment, including rituximab, could be proved a serious condition in patients who need specific treatment. In these patients desensitization protocols seem to be mandatory.

Indexed as

AnaphylaxisAntineoplastic AgentsLymphoma, Non-HodgkinPulmonary EdemaAged, 80 and overAntibodies, MonoclonalHumansMaleRituximabAntibodies, MonoclonalAntineoplastic AgentsRituximab

Identifiers

PMID34747381
PMCPMC10523046
OpenAlexW3211704108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.