Evidence map›Paper›PMID 34747333›Full record

ArticleGut microbes

Bacterial membrane vesicles and phages in blood after consumption of

Kevin Champagne-Jorgensen, Tamina A Jose, Andrew M Stanisz, M Firoz Mian, Alexander P Hynes, John Bienenstock

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Journal of microbiology and biotechnology · 2026
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  9. Article
  10. Article
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  12. Membrane Vesicles of Clostridioides difficile and Other Clostridial Species.Advances in experimental medicine and biology · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Extracellular membrane vesicles fromFrontiers in microbiology · 2022
    Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kevin Champagne-JorgensenNeuroscience Graduate Program, McMaster University, Hamilton, Canada.ORCID 0000-0002-1445-1449
Tamina A JoseDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
Andrew M StaniszBrain-Body Institute, St. Joseph's Healthcare Hamilton, Hamilton, Canada.
M Firoz MianBrain-Body Institute, St. Joseph's Healthcare Hamilton, Hamilton, Canada.
Alexander P HynesFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.
John BienenstockBrain-Body Institute, St. Joseph's Healthcare Hamilton, Hamilton, Canada.
St. Joseph’s Healthcare Hamilton · CAPopulation Health Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota have myriad roles in host physiology, development, and immunity. Though confined to the intestinal lumen by the epithelia, microbes influence distal systems via poorly characterized mechanisms. Recent work has considered the role of extracellular vesicles in interspecies communication, but whether they are involved in systemic microbe-host interaction is unclear. Here, we show that distinctive nanoparticles can be isolated from mouse blood within 2.5 h of consuming

Indexed as

AnimalsBacteriophagesBloodDendritic CellsExtracellular VesiclesInterleukin-8Intestinal MucosaLacticaseibacillus rhamnosusMaleMiceMice, Inbred BALB CProbioticsInterleukin-8Bacteriophagecommensalextracellular vesiclesinterleukin 10lactobacillusmicrobiomemicrobiota-gut-brain axismicrovesicleprobioticTLR2

Identifiers

PMID34747333
PMCPMC8583084
OpenAlexW3211543068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.