Evidence map›Paper›PMID 34747247›Full record

ArticleJournal of biomaterials applications2022

Further structural characterization of ovine forestomach matrix and multi-layered extracellular matrix composites for soft tissue repair.

Matthew J Smith, Sandi G Dempsey, Robert Wf Veale, Claudia G Duston-Fursman, Chloe A F Rayner, Chettha Javanapong, Dane Gerneke, Shane G Dowling, Brandon A Bosque, Tanvi Karnik and 11 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomaterials applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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  10. Application of pulsed electric field technology to skin engineering.Frontiers in bioengineering and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Matthew J SmithDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Sandi G DempseyDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Robert Wf VealeDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Claudia G Duston-FursmanDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Chloe A F RaynerDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Chettha JavanapongDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Dane GernekeAuckland Bioengineering Institute, 428614The University of Auckland, Auckland, New Zealand.
Shane G DowlingDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Brandon A BosqueDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Tanvi KarnikDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Michael J JerramDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Arun NagarajanDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Ravinder RajamDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Alister JowseyDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Samuel CutajarDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Isaac MasonDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Roderick G StanleyDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Andrew CampbellDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Jenny MalmstromDepartment of Chemical and Materials Engineering, 540736The University of Auckland, Auckland, New Zealand.
Chris H MillerDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.
Barnaby C H MayDepartment of Research and Clinical Development, Aroa Biosurgery Limited, Auckland, New Zealand.ORCID 0000-0001-9855-018X
University of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decellularized extracellular matrix (dECM)-based biomaterials are of great clinical utility in soft tissue repair applications due to their regenerative properties. Multi-layered dECM devices have been developed for clinical indications where additional thickness and biomechanical performance are required. However, traditional approaches to the fabrication of multi-layered dECM devices introduce additional laminating materials or chemical modifications of the dECM that may impair the biological functionality of the material. Using an established dECM biomaterial, ovine forestomach matrix, a novel method for the fabrication of multi-layered dECM constructs has been developed, where layers are bonded via a physical interlocking process without the need for additional bonding materials or detrimental chemical modification of the dECM. The versatility of the interlocking process has been demonstrated by incorporating a layer of hyaluronic acid to create a composite material with additional biological functionality. Interlocked composite devices including hyaluronic acid showed improved

Indexed as

Extracellular MatrixTissue ScaffoldsAnimalsBiocompatible MaterialsSheepTissue EngineeringBiocompatible Materialsangioconductioncell migrationdecellularized extracellular matrixhyaluronic acidkeratinocyteovine forestomach matrixwound healing

Identifiers

PMID34747247
PMCPMC8721687
OpenAlexW3212052402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.