ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022
A Skin-Interfaced, Miniaturized Microfluidic Analysis and Delivery System for Colorimetric Measurements of Nutrients in Sweat and Supply of Vitamins Through the Skin.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed.
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Skin-Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery.Advanced healthcare materials · 2026Article
- Lighting the Path to Precision Healthcare: Advances and Applications of Wearable Photonic Sensors.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Microfluidic technologies for wearable and implantable biomedical devices.Lab on a chip · 2025Review
- Advancements and Future Perspectives of Microfluidic Technology in Pediatric Healthcare.Smart medicine · 2025Review
- All-flexible chronoepifluidic nanoplasmonic patch for label-free metabolite profiling in sweat.Nature communications · 2025Article
- A bioinspired microfluidic wearable sensor for multiday sweat sampling, transport, and metabolic analysis.Science advances · 2025Article
- Hydrogels for Translucent Wearable Electronics: Innovations in Materials, Integration, and Applications.Gels (Basel, Switzerland) · 2025Review
- Electrophoretic digital colorimetry integrated with electrochemical sweat sensor.Science advances · 2025Article
- Soft, wearable, microfluidic system for fluorometric analysis of loss of amino acids through eccrine sweat.Lab on a chip · 2025Article
- Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration.Biomaterials · 2025Review
- A Highly Stable Electrochemical Sensor Based on a Metal-Organic Framework/Reduced Graphene Oxide Composite for Monitoring the Ammonium in Sweat.Biosensors · 2024Article
- Advanced Wearable Devices for Monitoring Sweat Biochemical Markers in Athletic Performance: A Comprehensive Review.Biosensors · 2024Review
- The future backbone of nutritional science: integrating public health priorities with system-oriented precision nutrition.The British journal of nutrition · 2024Review
- Revolutionary Point-of-Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery through Intelligent Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- In-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens.Nature communications · 2024Article
- Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring.Advanced sensor research · 2024Article
- Advancements in Skin-Mediated Drug Delivery: Mechanisms, Techniques, and Applications.Advanced healthcare materials · 2024Review
- A Miniaturized Wireless Micropump Enabled by Confined Acoustic Streaming.Research (Washington, D.C.) · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Nutrients play critical roles in maintaining core physiological functions and in preventing diseases. Technologies for delivering these nutrients and for monitoring their concentrations can help to ensure proper nutritional balance. Eccrine sweat is a potentially attractive class of biofluid for monitoring purposes due to the ability to capture sweat easily and noninvasively from nearly any region of the body using skin-integrated microfluidic technologies. Here, a miniaturized system of this type is presented that allows simple, rapid colorimetric assessments of the concentrations of multiple essential nutrients in sweat, simultaneously and without any supporting electronics - vitamin C, calcium, zinc, and iron. A transdermal patch integrated directly with the microfluidics supports passive, sustained delivery of these species to the body throughout a period of wear. Comparisons of measurement results to those from traditional lab analysis methods demonstrate the accuracy and reliability of this platform. On-body tests with human subjects reveal correlations between the time dynamics of concentrations of these nutrients in sweat and those of the corresponding concentrations in blood. Studies conducted before and after consuming certain foods and beverages highlight practical capabilities in monitoring nutritional balance, with strong potential to serve as a basis for guiding personalized dietary choices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.