ArticleLancet regional health. Americas2022
First and second COVID-19 waves in Brazil: A cross-sectional study of patients' characteristics related to hospitalization and in-hospital mortality.
Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed, 141 citations in OpenAlex.
- Pre-pandemic support for shared reading buffers adverse parenting impacts: an RCT in Brazil.Pediatric research · 2023Trial
- Efficacy and safety of HD-tDCS and respiratory rehabilitation for critically ill patients with COVID-19 The HD-RECOVERY randomized clinical trial.Brain stimulationTrial
- COVID-19 Mortality and Temporal Trends in a Mid-Sized Southern Brazilian City (2020-2023): A Population-Based Retrospective Study.Health science reports · 2026Article
- Antigenic remodeling of the SARS-CoV-2 Spike N-terminal domain links sequence variability to structural reorganization of a neutralizing antibody supersite.Frontiers in cellular and infection microbiology · 2026Article
- A countrywide study on post-COVID-19 condition in Brazil: the Epicovid 2.0.International journal of epidemiology · 2026Article
- Article
- Five Years of COVID-19 in Tocantins, Brazil: Epidemiology, Vaccination Impact, and SARS-CoV-2 Genomic Dynamics (2020-2025).Viruses · 2025Article
- Threat of coronavirus and depressive symptoms in adolescents: do 24-hour movement behaviors mediate this relationship?BMC public health · 2025Article
- Living With Persistent Respiratory Symptoms of Long COVID: Qualitative Study Among Brazilian Adults 12 Months After Acute Infection.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Neutrophil Extracellular Trap Markers in Post Mortem Lung Biopsies from COVID-19 Patients.International journal of molecular sciences · 2025Article
- Clinical management and outcomes in severe COVID-19: acute respiratory distress syndrome across two waves.Revista da Escola de Enfermagem da U S P · 2025Article
- Hand hygiene adherence in intensive care units: comparison before and during the COVID-19 pandemic in a municipality of São Paulo state.Einstein (Sao Paulo, Brazil) · 2025Article
- COVID-19 case fatality ratio and survival among hospitalized adults in Goiás, 2020: a cohort study.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Psychosocial work aspects, work ability, mental health and SARS-CoV-2 infection rates of on-site and remote Brazilian workers during the COVID-19 pandemic - a longitudinal study.BMC public health · 2024Article
- Associations between epidemiological and laboratory parameters and disease severity in hospitalized patients with COVID-19 during first and second epidemic waves in middle south Mato Grosso.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Managing long COVID symptoms and accessing health services in Brazil: A grounded theory analysis.Heliyon · 2024Article
- Hospitalisations and fatality due to respiratory diseases according to a national database in Brazil: a longitudinal study.BMJ open respiratory research · 2024Article
- Impact of social distancing from the COVID-19 pandemic on the immuno-inflammatory response of older adults.BMC geriatrics · 2024Article
- Social inequalities in self-reported SARS-CoV-2 infection in Brazilian adults: PNAD COVID-19.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Article
- Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBackground The second wave of the COVID-19 pandemic was more aggressive in Brazil compared to other countries around the globe. Considering the Brazilian peculiarities, we analyze the in-hospital mortality concerning socio-epidemiological characteristics of patients and the health system of all states during the first and second waves of COVID-19.
methodsWe performed a cross-sectional study of hospitalized patients with positive RT-PCR for SARS-CoV-2 in Brazil. Data was obtained from the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) and comprised the period from February 25, 2020, to April 30, 2021, separated in two waves on November 5, 2020. We performed a descriptive study of patients analyzing socio-demographic characteristics, symptoms, comorbidities, and risk factors stratified by age. In addition, we analyzed in-hospital and intensive care unit (ICU) mortality in both waves and how it varies in each Brazilian state.
findingsBetween February 25, 2020 and April 30, 2021, 678 235 patients were admitted with a positive RT-PCR for SARS-CoV-2, with 325 903 and 352 332 patients for the first and second wave, respectively. The mean age of patients was 59
interpretationWe observed a more considerable burden on the Brazilian hospital system throughout the second wave. Furthermore, the north and northeast of Brazil, which present lower Human Development Indexes, concentrated the worst in-hospital mortality rates. The highest mortality rates are also shown among vulnerable social groups. Finally, we believe that the results can help to understand the behavior of the COVID-19 pandemic in Brazil, helping to define public policies, allocate resources, and improve strategies for vaccination of priority groups.
fundingCoordinating Agency for Advanced Training of Graduate Personnel (CAPES) (C.F. 001), and National Council for Scientific and Technological Development (CNPq) (No. 309537/2020-7).
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