ReviewInnovation (Cambridge (Mass.))2021
Exposome in human health: Utopia or wonderland?
Review in Innovation (Cambridge (Mass.)), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06090747 (Efecto de Una intervención Multidisciplinaria de Estilo de Vida Sobre el Exposoma de Pacientes premenopáusicas Con cáncer de Mama Estadios I-III.), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efecto de Una intervención Multidisciplinaria de Estilo de Vida Sobre el Exposoma de Pacientes premenopáusicas Con cáncer de Mama Estadios I-III.
Who cites it
22 citing papers in PubMed.
- The Human Exposome: Integrating the Environment, Human Health, and Society for the Next 60 years.Environmental science & technology · 2026Review
- The Integrated Human System Framework: A Conceptual Model of Skin as a Biological Interface Across Health and Well-Being.Clinical, cosmetic and investigational dermatology · 2026Review
- The impact of the Social Exposome in Cardiovascular Health and Disease.Journal of precision medicine (Amsterdam, Netherlands) · 2025Article
- Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era.Environment & health (Washington, D.C.) · 2025Article
- De Novo exposomic geospatial assembly of chronic disease regions with machine learning & network analysis.EBioMedicine · 2025Article
- Association between blood essential metal elements in early pregnancy and gestational diabetes mellitus.Frontiers in nutrition · 2025Article
- Perspective on the ethics of AI at the intersection of nutrition and behaviour change.Frontiers in aging · 2025Article
- Observed Effects on Very Early Pregnancy Linked to Ambient PMEnvironment & health (Washington, D.C.) · 2024Article
- Emerging contaminants: A One Health perspective.Innovation (Cambridge (Mass.)) · 2024Review
- Geospatial Science for the Environmental Epidemiology of Cancer in the Exposome Era.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- The science of uncertainty guides fetal-neonatal neurology principles and practice: diagnostic-prognostic opportunities and challenges.Frontiers in neurology · 2024Review
- Ambient air pollution and infant health: a narrative review.EBioMedicine · 2023Review
- Examination of the exposome in an animal model: The impact of high fat diet and rat strain on local and systemic immune markers following occupational welding fume exposure.Toxicology and applied pharmacology · 2023Article
- HExpPredict:Environmental health perspectives · 2023Article
- Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice.Frontiers in neurology · 2023Review
- Exposomics as a tool to investigate differences in health and disease by sex and gender.Exposome · 2023Review
- Whole Person Modeling: a transdisciplinary approach to mental health research.Discover mental health · 2023Review
- A review on the application of the exposome paradigm to unveil the environmental determinants of age-related diseases.Human genomics · 2022Review
- Time to Consider the "Exposome Hypothesis" in the Development of the Obesity Pandemic.Nutrients · 2022Review
- PMInnovation (Cambridge (Mass.)) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current human exposome primarily emphasizes the total environmental exposure during an entire life. The characteristics of "lifelong" and "all environmental factors" make it very challenging to bring the exposomic study into real-life applications. Herein, we mainly discuss the typical application scenarios of exposomics and how to conduct an exposomic study to establish relationships between the exposome and human health. To increase the feasibility and efficiency, we propose that (1) an exposomic study can start with health events during critical-window periods; (2) both data- and hypothesis-driven exposomics should be combined to prioritize the risk of environmental factors; and (3) reliable statistical analysis of high-dimensional data of external and internal exposure factors are urgently needed. With standardization of the exposomic study, it will be critical to build a "wonderland" for human health.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.