Evidence map›Paper›PMID 34746742›Full record

ArticleClinical parkinsonism & related disorders2021

Transcranial and muscular single-pulse magnetic stimulation is efficient on motor functional neurological disorders by the feedback of induced muscle contractions - A retrospective case series.

Mickael Bonnan

Open access · goldAbstract read
In one paragraph

Article in Clinical parkinsonism & related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Mickael BonnanService de Neurologie, Centre Hospitalier de Pau, 64000 PAU, France.
Centre Hospitalier De Pau · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMotor functional neurological disorders (mFNDs) are improved by repetitive transcranial magnetic stimulation (rTMS), which is thought to involve cortical modulation. We examined the outcome of a rapid TMS procedure.

methodsSingle-center retrospective case series including 41 consecutive patients suffering from mFNDs and receiving a combination of motor-evoked potentials (MEP), TMS and/or muscle stimulation.

resultsMEP and additional TMS were administered in 35 patients, sometimes with rescue by muscle stimulation. Magnetic muscle stimulation was given in 6 patients, sometimes with rescue by TMS. Complete immediate recovery was obtained in 65.9 % of the 41 patients, but the outcome of mFNDs after one year was poor. Treatment by TMS (n = 19) or by muscle stimulation (n = 4) given alone were associated with 78.9 % and 75 % of complete immediate recovery, respectively.

conclusionsA rapid easy-to-perform TMS procedure obtained a high rate of immediate complete recovery in mFND. Clinical recovery was improved but was also obtained by direct magnetic stimulation of the paralyzed muscles. SIGNIFICANCE: TMS-induced recovery of mFND may not involve cortical modulation but could rather occur through reinforcement of the suggestion. Magnetic-induced muscle twitches may facilitate the self-expectation of motor recovery and could unlock the motor symptoms of mFND.

Indexed as

Conversion disorderFunctional neurological disorderMagnetic field therapyMotor-evoked potentialsSuggestionTranscranial magnetic stimulation

Identifiers

PMID34746742
PMCPMC8554265
OpenAlexW3209792918

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.