ArticleEClinicalMedicine2021
Subtypes of gestational diabetes and future risk of pre-diabetes or diabetes.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 31 citations in OpenAlex.
- Gestational Diabetes Mellitus Subtypes and Maternal Cardiometabolic Outcomes 10-14 Years After Delivery.Diabetes care · 2026Article
- Data-Driven Phenotypic Clusters of Gestational Diabetes Mellitus and Associations With Risk of Perinatal Complications and Postpartum Diabetes.Diabetes care · 2026Article
- Gestational Diabetes and Postpartum Cardiovascular, Kidney, and Metabolic Disorders.JAMA network open · 2026Article
- Gestational Diabetes Associated with Postpartum NAFLD Risk Meta-Analysis: Evidence for Sustained Metabolic Dysfunction Beyond Pregnancy.Journal of clinical medicine · 2026Review
- Early pregnancy meal tolerance test responses and their association with later insulin sensitivity in overweight and obese women: an exploratory analysis.Frontiers in endocrinology · 2026Observational
- Extracellular Vesicles in Gestational Diabetes Mellitus: Pathogenesis, Diagnosis, and Therapy.International journal of nanomedicine · 2026Review
- Gestational diabetes mellitus subtypes: from one-size-fits-all to precision medicine.Hormones (Athens, Greece) · 2025Review
- Early Postpartum Glucose Tolerance Reclassification by Gestational Diabetes Subtype.JAMA network open · 2025Article
- Gestational diabetes mellitus subtypes according to oral glucose tolerance test and pregnancy outcomes.Endocrine · 2025Article
- Article
- Serum endotrophin relates to blood pressure in young South Asian women but not White women: evidence of ethnic variation in its early vascular implications.BMC cardiovascular disorders · 2025Article
- Diabetes polygenic risk scores and maternal characteristics in Hoosier Moms Cohort participants.Pregnancy (Hoboken, N.J.) · 2025Article
- Metabolic Phenotypes of Women with Gestational Diabetes Mellitus Affect the Risk of Adverse Pregnancy Outcomes.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Early Postpartum Metabolic Heterogeneity Among Women Who Progressed to Type 2 Diabetes After Gestational Diabetes: A Prospective Cohort.Diabetes/metabolism research and reviews · 2025Article
- Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy.BMJ open diabetes research & care · 2024Article
- Clinical Risk Factors and First Gestational 75 g OGTT May Predict Recurrent and New-Onset Gestational Diabetes in Multiparous Women.Journal of clinical medicine · 2024Article
- Postpartum development of metabolic dysfunction-associated steatotic liver disease in a lean mouse model of gestational diabetes mellitus.Scientific reports · 2024Article
- Clinical and Metabolic Characterization of Women With Gestational Diabetes Mellitus Within the First Year Postpartum.Journal of the Endocrine Society · 2024Article
- Postpartum glucose intolerance after gestational diabetes mellitus: tailored prediction according to data-driven clusters and BMI-categories.Frontiers in endocrinology · 2024Article
- Gestational Diabetes Mellitus Subtypes Classified by Oral Glucose Tolerance Test and Maternal and Perinatal Outcomes: Results of a Mexican Multicenter Prospective Cohort Study "Cuido Mi Embarazo".Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have suggested that gestational diabetes (GDM) is a heterogeneous condition with distinct subtypes determined by whether the predominant metabolic abnormality is impaired insulin sensitivity or deficient insulin secretion. However, it is not known if the elevated future risk of pre-diabetes/diabetes associated with GDM varies according to these subtypes. Thus, we sought to evaluate maternal metabolic function in the 1st year postpartum in relation to GDM subtypes.
methodsIn this prospective cohort study conducted in Toronto, Canada, 613 women underwent GDM screening by oral glucose tolerance test (OGTT) in pregnancy, followed by repeat OGTT at both 3-months and 12-months postpartum between 09/2003 and 03/2016. The antepartum OGTT identified 3 groups of women: GDM with predominant sensitivity defect (GDM-sensitivity), GDM with predominant secretion defect (GDM-secretion), and non-GDM.
findingsAntepartum findings persisted after pregnancy, with lower insulin sensitivity in GDM-sensitivity (Matsuda index; HOMA-IR) and lower insulin secretion in GDM-secretion (Stumvoll first-phase; insulinogenic index (IGI)) at both 3-months and 12-months (all
interpretationBeta-cell dysfunction, glycemia and incident pre-diabetes/diabetes do not vary between GDM subtypes in the 1st year postpartum.
fundingCanadian Institutes of Health Research; Diabetes Canada.
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