Evidence map›Paper›PMID 34746699›Full record

ArticleiScience2021

A Ayanna Wade, Jelle van den Ameele, Seth W Cheetham, Rebecca Yakob, Andrea H Brand, Alex S Nord

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Life science alliance · 2024
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

A Ayanna WadeDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, CA 95616, USA.
Jelle van den AmeeleThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 1TN, UK.
Seth W CheethamThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 1TN, UK.
Rebecca YakobThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 1TN, UK.
Andrea H BrandThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 1TN, UK.
Alex S NordDepartment of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, CA 95616, USA.
University of Cambridge · GBUniversity of California, Davis · US

Funding

UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Functional Elucidation of the Sequence-Encoded Regulatory Activity of Enhancers in Vivo in the BrainR35GM119831 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Alexander Nord · 2016 to 2026
$3.9M
Causal biology of Chd8 haploinsufficiency in complex brain disordersR01MH120513 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NORD, ALEXANDER · 2019 to 2023
$2.3M
Chd8 Dosage-Sensitivity in Mature Neurons Contributes to ASD-Associated PathologyF31MH119789 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WADE, ALEXANDRIA AYANNA · 2019 to 2020
$56k
NIGMS NIH HHS R35 GM119831NIGMS NIH HHS T32 GM007377NIMH NIH HHS F31 MH119789NIMH NIH HHS R01 MH120513Wellcome Trust 092096Wellcome Trust 103792Wellcome Trust 105839
6 · The paper itself

Abstract

Genetic studies of autism have revealed causal roles for chromatin remodeling gene mutations. Chromodomain helicase DNA binding protein 8 (

Indexed as

BiotechnologyGenomic analysisGenomicsMolecular neuroscience

Identifiers

PMID34746699
PMCPMC8551073
OpenAlexW3203426523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.