Evidence map›Paper›PMID 34746627›Full record

ArticleNetwork neuroscience (Cambridge, Mass.)2021

Regional radiomics similarity networks (R2SNs) in the human brain: Reproducibility, small-world properties and a biological basis.

Kun Zhao, Qiang Zheng, Tongtong Che, Martin Dyrba, Qiongling Li, Yanhui Ding, Yuanjie Zheng, Yong Liu, Shuyu Li

Abstract read
In one paragraph

Article in Network neuroscience (Cambridge, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

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  17. Brain connectome from neuronal morphology.Network neuroscience (Cambridge, Mass.) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kun ZhaoSchool of Biological Science & Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Qiang ZhengSchool of Computer and Control Engineering, Yantai University, Yantai, China.
Tongtong CheSchool of Biological Science & Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Martin DyrbaGerman Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Qiongling LiSchool of Biological Science & Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Yanhui DingSchool of Information Science and Engineering, Shandong Normal University, Jinan, China.
Yuanjie ZhengSchool of Information Science and Engineering, Shandong Normal University, Jinan, China.
Yong LiuSchool of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Shuyu LiSchool of Biological Science & Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.ORCID https://orcid.org/0000-0002-3459-6821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A structural covariance network (SCN) has been used successfully in structural magnetic resonance imaging (sMRI) studies. However, most SCNs have been constructed by a unitary marker that is insensitive for discriminating different disease phases. The aim of this study was to devise a novel regional radiomics similarity network (R2SN) that could provide more comprehensive information in morphological network analysis. R2SNs were constructed by computing the Pearson correlations between the radiomics features extracted from any pair of regions for each subject (AAL atlas). We further assessed the small-world property of R2SNs, and we evaluated the reproducibility in different datasets and through test-retest analysis. The relationships between the R2SNs and general intelligence/interregional coexpression of genes were also explored. R2SNs could be replicated in different datasets, regardless of the use of different feature subsets. R2SNs showed high reproducibility in the test-retest analysis (intraclass correlation coefficient > 0.7). In addition, the small-word property (σ > 2) and the high correlation between gene expression (

Indexed as

Biological basisRegional radiomics similarity networksReproducibilitySmall-world

Identifiers

PMID34746627
PMCPMC8567836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.