Evidence map›Paper›PMID 34746505›Full record

ArticleJournal of the anus, rectum and colon2021

Clinical Features and Therapeutic Outcomes of Post-colectomy Enteritis with Ulcerative Colitis.

Yuki Horio, Motoi Uchino, Kazutoshi Hori, Kurando Kusunoki, Tomohiro Minagawa, Ryuichi Kuwahara, Kozo Kataoka, Naohito Beppu, Masataka Ikeda, Hiroki Ikeuchi

Open access · goldAbstract read
In one paragraph

Article in Journal of the anus, rectum and colon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yuki HorioDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Motoi UchinoDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Kazutoshi HoriDepartment of Intestinal Inflammation Research, Hyogo College of Medicine, Hyogo, Japan.
Kurando KusunokiDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Tomohiro MinagawaDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Ryuichi KuwaharaDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Kozo KataokaDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Naohito BeppuDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Masataka IkedaDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Hiroki IkeuchiDepartment of Gastroenterological Surgery, Hyogo College of Medicine, Hyogo, Japan.
Hyogo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFew reports are available on post-colectomy enteritis (PCE) with ulcerative colitis (UC), which can be severe and sometimes fatal. The clinical characteristics are unclear, and treatment and diagnosis protocols have not been established. We aimed to investigate the incidence, clinical characteristics, diagnostic criteria, and therapeutic outcomes of PCE in this study.

methodsPatients with UC who underwent colectomy between April 2010 and December 2019 were included in this study. We retrospectively analyzed patients who developed PCE and excluded patients with other forms of enteritis.

resultsWe performed 829 colectomies because of a preoperative diagnosis of UC. Eleven and four patients were diagnosed with Crohn's disease and indeterminate colitis after surgery, respectively; 22 patients developed enteritis in the perioperative period. We excluded six patients with backwash ileitis, five with prepouch ileitis, three with infectious enteritis, and one with ischemic enteritis. In total, 7/814 (0.8%) patients developed PCE. All patients with PCE had pancolitis. PCE was observed a median of 33 (12-248) days after surgery. Endoscopy showed friable and granular mucosa. The extent of disease included various types such as pan-enteritis with diffuse type, pan-enteritis and mild inflammation in the middle ileum, and only ileitis. Gastroduodenitis-associated UC developed in 6/7 cases. All patients improved with tumor necrosis factor alpha (TNFα) antagonists even if TNFα antagonists had not been effective for colitis.

conclusionsPCE was rare. The mucosal endoscopic findings were similar to those of UC, and the extent of disease varied. TNFα antagonist administration for PCE was effective.

Indexed as

post-colectomy enteritissmall bowel lesiontumor necrosis factor alpha antagonistsulcerative colitis

Identifiers

PMID34746505
PMCPMC8553349
OpenAlexW3209084676

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.