Evidence map›Paper›PMID 34746473›Full record

ArticleHeliyon2021

Layer-by-layer films of polysaccharides modified with poly(N-vinylpyrrolidone) and poly(vinyl alcohol).

Kanstantsin S Livanovich, Anastasiya A Sharamet, Anna N Shimko, Tatsiana G Shutava

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kanstantsin S LivanovichInstitute of Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk, Belarus.
Anastasiya A SharametInstitute of Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk, Belarus.
Anna N ShimkoCenter for Analytical Spectral Measurements, B.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, Belarus.
Tatsiana G ShutavaInstitute of Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk, Belarus.
Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus · BYNational Academy of Sciences of Belarus · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-grafted copolymers of chitosan (460 kDa) with poly(N-vinylpyrrolidone) (2.4 kDa) or poly(vinyl alcohol) (2.0 ​kDa) as side chains were synthesized. Depending on the polymer-to-chitosan mass ratio the degree of amino group substitution with side chains in chitosan backbone was varied in the range of 0.01-0.33. Layer-by-layer films consisted of copolymers and dextran sulfate as polyanion were obtained. Thickness, hydrophilicity, and morphology of the films were investigated using QCM, UV-vis spectrophotometry, AFM, and contact angle measurements. The obtained films show enhanced protein-repellent properties in fetal bovine serum medium. The mass of adsorbed proteins on LbL films based on copolymer with a degree of substitution of 0.2 decreases by 50 ​% compared to unmodified chitosan. Protein-repellent properties of copolymer-based films are common for LbL films of grafted chitosan copolymers and depend on hydrophilic side chain density on the surface.

Indexed as

Chitosan copolymerLayer-by-layer assemblyPoly(N-vinylpyrrolidone)Poly(vinyl alcohol)Protein adsorption

Identifiers

PMID34746473
PMCPMC8555284
OpenAlexW3206254493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.