Evidence map›Paper›PMID 34746111›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Antifungal Activity of ToAP2D Peptide Against

Tianyi Yan, Fuqiu Li, Jinran Li, Feng Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Structure, biosynthesis, and bioactivity of nostolysamides.bioRxiv : the preprint server for biology · 2026
    Article
  4. Antimicrobial peptides from arthropod venoms exhibit activity againstThe journal of venomous animals and toxins including tropical diseases · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Nd:YAG1064nm laser functions againstFrontiers in microbiology · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Emerging Antifungal Targets and Strategies.International journal of molecular sciences · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tianyi YanDepartment of Dermatology, Second Hospital of Jilin University, Changchun, China.
Fuqiu LiDepartment of Dermatology, Second Hospital of Jilin University, Changchun, China.
Jinran LiDepartment of Dermatology, Second Hospital of Jilin University, Changchun, China.
Feng ChenDepartment of Dermatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Second Affiliated Hospital of Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improving clinical efficacy and reducing treatment time have been the focus of sporotrichosis therapy. Antimicrobial peptides ToAP2A, ToAP2C, and ToAP2D were synthesized on the basis of ToAP2 (AP02759), a peptide derived from the antimicrobial peptide database by the database filtering technology, and their physicochemical characteristics were analyzed. Compared with template peptide ToAP2, the modified peptides had much shorter length, lower molecular weight but significantly greater stability, which in return resulted in increases in the aliphatic index, hydrophilicity, and protein binding ability. Here, we show that the three derived peptides inhibit the growth of

Indexed as

anti-fungal activityantimicrobial peptideapoptosisdesign and modificationSporothrix globosa

Identifiers

PMID34746111
PMCPMC8566951
OpenAlexW3210459288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.