Evidence map›Paper›PMID 34746023›Full record

ReviewFrontiers in cellular and infection microbiology2021

The Fecal Microbiota Transplantation: A Remarkable Clinical Therapy for Slow Transit Constipation in Future.

Jiafei Liu, Liqiang Gu, Mingqing Zhang, Shiwu Zhang, Min Wang, Yu Long, Xipeng Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Journal of traditional and complementary medicine · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Current Applications of Fecal Microbiota Transplantation in Functional Constipation.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiafei LiuDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Liqiang GuDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Mingqing ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Shiwu ZhangDepartment of Pathology, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Min WangKey Laboratory of Molecular Microbiology and Technology, Ministry of Education, TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
Yu LongDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Xipeng ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Nankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Slow transit constipation is a common condition that would be difficult to treat in clinical practice with a widespread incidence in the population. Pharmacotherapy and surgery are common treatment modalities. However, the clinical effect is limited, and patients still suffer from it. As the researchers strived in this field for decades, the profound relationship between slow transit constipation and fecal microbiota transplantation has comprehensively been sustained. It is very pivotal to maintain intestinal homeostasis, the structure function and metabolic function of symbiotic bacteria, which can inhibit the engraftment of intestinal pathogens. This mini review explains the treatment effects and possible mechanisms of the fecal microbiota transplantation in treating slow transit constipation. Simultaneously, it is found that there is significant improvement in the disease by adjusting the intestinal microbes like fecal microbiota transplantation. Fecal microbiota transplantation has efficient therapeutic effects in slow transit constipation compared with traditional therapies.

Indexed as

ConstipationFecal Microbiota TransplantationBacteriaHumansfecal microbiota transplantationintestinal motilityintestinal neuronshort-chain fatty acidsslow transit constipation

Identifiers

PMID34746023
PMCPMC8569429
OpenAlexW3208414346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.