Evidence map›Paper›PMID 34745866›Full record

ArticleRespiratory medicine case reports2021

Exacerbation of nontuberculous mycobacterial pulmonary disease in a patient with advanced non-small-cell lung cancer during treatment with PD-1 inhibitor and chemotherapy.

Mariko Okamoto, Young Hak Kim, Aiko Ouchi, Takashi Yamaoka, Natsuhiko Iwamoto, Shigeaki Iwatsubo, Kanoko Matsumura, Miho Nakamura, Yasuo Kin, Yoshitaka Shiina and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respiratory medicine case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. PD-1 deficiency exacerbatesFrontiers in immunology · 2026
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mariko OkamotoDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Young Hak KimDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Aiko OuchiDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Takashi YamaokaDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Natsuhiko IwamotoDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Shigeaki IwatsuboDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Kanoko MatsumuraDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Miho NakamuraDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Yasuo KinDepartment of Respiratory Surgery, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Yoshitaka ShiinaDepartment of Respiratory Surgery, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Yasuhiro FunadaDepartment of Respiratory Medicine, Takatsuki General Hospital, Takatsuki, Osaka, Japan.
Takatsuki General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old man visited our hospital due to an abnormal shadow on a chest X-ray. Chest CT showed a mass shadow in his left lower lobe accompanied by an infiltrative shadow in the right upper lobe. Thorough examination led to a diagnosis of pulmonary squamous cell lung carcinoma, stage IIIB (T3N2M0). Combination treatment with chemotherapy and programmed cell death receptor 1 (PD-1) inhibitor was started, leading to a partial response. However, his pre-existing pulmonary infiltrative shadow progressed during the maintenance treatment with PD-1 inhibitor, and sputum culture revealed

Indexed as

ExacerbationImmune checkpoint inhibitorNon-small-cell lung cancerNontuberculous mycobacterial pulmonary diseasePD-1 inhibitor

Identifiers

PMID34745866
PMCPMC8555433
OpenAlexW3209004255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.