Evidence map›Paper›PMID 34745816›Full record

Article3 Biotech2021

Chemoprophylaxis under sporozoites-lumefantrine (CPS-LMF) immunization induce protective immune responses against

Arif Jamal Siddiqui, Jyoti Bhardwaj, Walid Sabri Hamadou, Manish Goyal, Syed Amir Ashraf, Sadaf Jahan, Arshad Jamal, Pankaj Sharma, Manojkumar Sachidanandan, Riadh Badraoui and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Host-parasite interactions duringFrontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Arif Jamal Siddiqui *Department of Biology, College of Science, University of Ha'il, PO Box 2440, Ha'il, Saudi Arabia.ORCID 0000-0002-6236-0920
Jyoti Bhardwaj *School of Medicine, Indiana University, Indianapolis, IN USA.
Walid Sabri HamadouDepartment of Biology, College of Science, University of Ha'il, PO Box 2440, Ha'il, Saudi Arabia.
Manish GoyalMolecular Parasitology and Immunology Division, CSIR-Central Drug Research Institute, Lucknow, 226031 India.
Syed Amir AshrafDepartment of Clinical Nutrition, College of Applied Medial Sciences, University of Hail, PO Box 2440, Ha'il, Saudi Arabia.
Sadaf JahanDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majma'ah, 11952 Saudi Arabia.
Arshad JamalDepartment of Biology, College of Science, University of Ha'il, PO Box 2440, Ha'il, Saudi Arabia.
Pankaj SharmaMolecular Parasitology and Immunology Division, CSIR-Central Drug Research Institute, Lucknow, 226031 India.
Manojkumar SachidanandanDepartment of Oral Radiology, College of Dentistry, University of Hail, PO Box 2440, Ha'il, Saudi Arabia.
Riadh BadraouiDepartment of Biology, College of Science, University of Ha'il, PO Box 2440, Ha'il, Saudi Arabia.
Mohd AdnanDepartment of Biology, College of Science, University of Ha'il, PO Box 2440, Ha'il, Saudi Arabia.
University of Ha'il · SACentral Drug Research Institute · INBoston Children's Hospital · USMajmaah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria represents one of the major life-threatening diseases that poses a huge socio-economic impact, worldwide. Chemoprophylaxis vaccination using a relatively low number of wild-type infectious sporozoites represents an attractive and effective vaccine strategy against malaria. However, the role of immune responses to pre-erythrocytic versus blood-stage parasites in protection against different antimalarial drugs remains unclear. Here, in the present study, we explored the immune responses against the repetitive inoculation of live SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-021-03022-0.

Indexed as

ChemoprophylaxisCPS-immunizationCytokines responseLumefantrinemRNA expressionPlasmodium yoelii

Identifiers

PMID34745816
PMCPMC8526652
OpenAlexW3205556118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.