Evidence map›Paper›PMID 34745748›Full record

ArticleBiomedical optics express2021

Compressed sensing time-resolved spectrometer for quantification of light absorbers in turbid media.

Seva Ioussoufovitch, David Jonathan Fulop Cohen, Daniel Milej, Mamadou Diop

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Seva IoussoufovitchWestern University, Faculty of Engineering, School of Biomedical Engineering, Collaborative Training Program in Musculoskeletal Health Research, Bone & Joint Institute, 1151 Richmond St., London, N6A 5C1, Canada.ORCID https://orcid.org/0000-0001-8077-4847
David Jonathan Fulop CohenWestern University, Schulich School of Medicine & Dentistry, Department of Medical Biophysics, 1151 Richmond St., London, N6A 5C1, Canada.
Daniel MilejWestern University, Schulich School of Medicine & Dentistry, Department of Medical Biophysics, 1151 Richmond St., London, N6A 5C1, Canada.ORCID https://orcid.org/0000-0003-3173-0834
Mamadou DiopWestern University, Faculty of Engineering, School of Biomedical Engineering, Collaborative Training Program in Musculoskeletal Health Research, Bone & Joint Institute, 1151 Richmond St., London, N6A 5C1, Canada.ORCID https://orcid.org/0000-0003-1244-7830
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Time-resolved (TR) spectroscopy is well-suited to address the challenges of quantifying light absorbers in highly scattering media such as living tissue; however, current TR spectrometers are either based on expensive array detectors or rely on wavelength scanning. Here, we introduce a TR spectrometer architecture based on compressed sensing (CS) and time-correlated single-photon counting. Using both CS and basis scanning, we demonstrate that-in homogeneous and two-layer tissue-mimicking phantoms made of Intralipid and Indocyanine Green-the CS method agrees with or outperforms uncompressed approaches. Further, we illustrate the superior depth sensitivity of TR spectroscopy and highlight the potential of the device to quantify absorption changes in deeper (>1 cm) tissue layers.

Identifiers

PMID34745748
PMCPMC8547999
OpenAlexW3200314154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.