Evidence map›Paper›PMID 34745746›Full record

ArticleBiomedical optics express2021

Bayesian deep learning for reliable oral cancer image classification.

Bofan Song, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick, Shubha Gurudath, Subhashini Raghavan, Imchen Tsusennaro and 13 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Weakly Supervised Learning of Oral Cavity Images for Separating Precancer from Cancer.IEEE International Conference on Omni-layer Intelligent Systems : COINS. IEEE International Conference on Omni-layer Intelligent Systems · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Oral Cancer Detection By Using Tabular Data Synthesis and Classification.Proceedings ... ICDM workshops. IEEE International Conference on Data Mining · 2025
    Article
  10. Detecting Oral Cancer Using Tabular Deep Learning.IEEE International Conference on Omni-layer Intelligent Systems : COINS. IEEE International Conference on Omni-layer Intelligent Systems · 2025
    Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Bofan SongWyant College of Optical Sciences, The University of Arizona, Tucson, Arizona 85721, USA.
Sumsum SunnyMazumdar Shaw Medical Centre, Bangalore, India.
Shaobai LiWyant College of Optical Sciences, The University of Arizona, Tucson, Arizona 85721, USA.
Keerthi GurushanthKLE Society Institute of Dental Sciences, Bangalore, India.
Pramila MendoncaMazumdar Shaw Medical Foundation, Bangalore, India.
Nirza MukhiaKLE Society Institute of Dental Sciences, Bangalore, India.
Sanjana PatrickBiocon Foundation, Bangalore, India.
Shubha GurudathKLE Society Institute of Dental Sciences, Bangalore, India.
Subhashini RaghavanKLE Society Institute of Dental Sciences, Bangalore, India.
Imchen TsusennaroChristian Institute of Health Sciences and Research, Dimapur, India.
Shirley T LeivonChristian Institute of Health Sciences and Research, Dimapur, India.
Trupti KolurMazumdar Shaw Medical Foundation, Bangalore, India.
Vivek ShettyMazumdar Shaw Medical Foundation, Bangalore, India.
Vidya R BushanMazumdar Shaw Medical Foundation, Bangalore, India.
Rohan RameshChristian Institute of Health Sciences and Research, Dimapur, India.
Tyler PetersonWyant College of Optical Sciences, The University of Arizona, Tucson, Arizona 85721, USA.ORCID https://orcid.org/0000-0002-3637-9134
Vijay PillaiMazumdar Shaw Medical Foundation, Bangalore, India.
Petra Wilder-SmithBeckman Laser Institute and Medical Clinic, University of California, Irvine, California 92697, USA.
Alben SigamaniMazumdar Shaw Medical Foundation, Bangalore, India.
Amritha SureshMazumdar Shaw Medical Centre, Bangalore, India.
Moni Abraham KuriakoseCochin Cancer Research Center, Kochi, India.
Praveen BirurKLE Society Institute of Dental Sciences, Bangalore, India.
Rongguang LiangWyant College of Optical Sciences, The University of Arizona, Tucson, Arizona 85721, USA.

Funding

Multimodal Intraoral Imaging System for Oral Cancer Detection and Diagnosis in Low Resource SettingR01DE030682 · NIDCR · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2021 to 2025
$2.8M
Low-cost Mobile Oral Cancer Screening for Low Resource SettingUH3CA239682 · NCI · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2018 to 2020
$2.5M
Low-cost Mobile Oral Cancer Screening for Low Resource SettingUH2EB022623 · NIBIB · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2016 to 2017
$996k
NCI NIH HHS UH3 CA239682NIBIB NIH HHS UH2 EB022623NIDCR NIH HHS R01 DE030682
6 · The paper itself

Abstract

In medical imaging, deep learning-based solutions have achieved state-of-the-art performance. However, reliability restricts the integration of deep learning into practical medical workflows since conventional deep learning frameworks cannot quantitatively assess model uncertainty. In this work, we propose to address this shortcoming by utilizing a Bayesian deep network capable of estimating uncertainty to assess oral cancer image classification reliability. We evaluate the model using a large intraoral cheek mucosa image dataset captured using our customized device from high-risk population to show that meaningful uncertainty information can be produced. In addition, our experiments show improved accuracy by uncertainty-informed referral. The accuracy of retained data reaches roughly 90% when referring either 10% of all cases or referring cases whose uncertainty value is greater than 0.3. The performance can be further improved by referring more patients. The experiments show the model is capable of identifying difficult cases needing further inspection.

Identifiers

PMID34745746
PMCPMC8547976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.