ArticleBiomedical optics express2021
Heterodyne Brillouin microscopy for biomechanical imaging.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Viscoelasticity in 3D Cell Culture and Regenerative Medicine: Measurement Techniques and Biological Relevance.ACS materials Au · 2024Review
- Brillouin microscopy.Nature reviews. Methods primers · 2024Article
- Non-contact and label-free biomechanical imaging: Stimulated Brillouin microscopy and beyond.Frontiers in physics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microscopic variations in material stiffness play a vital role in cellular scale biomechanics, but are difficult to measure in a natural 3D environment. Brillouin microscopy is a promising technology for such applications, providing non-contact label-free measurement of longitudinal modulus at microscopic resolution. Here we develop heterodyne detection to measure Brillouin scattering signals in a confocal microscope setup, providing sensitive detection with excellent frequency resolution and robust operation in the presence of stray light. The functionality of the microscope is characterized and validated, and the imaging capability demonstrated by imaging structure within both a fibrin fiber network and live cells.
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Registered trials
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